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烯丙孕素

烯丙孕素用途

类别：有毒物品
可燃性危险特性：可燃;燃烧产生刺激烟雾
储运特性：库房通风低温干燥; 与食品原料分开存放
灭火剂：干粉、泡沫、砂土、二氧化碳, 雾状水

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烯丙孕素名称

[ CAS 号 ]:
850-52-2

[ 中文名 ]:
四烯雌酮

[ 英文名 ]:
Altrenogest

[中文别名 ]:

[英文别名 ]:

Allyltrenbolone
r2267
17α-Allyl-17-hydroxyestra-4,9,11-trien-3-one
altregonest
Altrenogest
REGU-MATE
17-allyltrenbolone
ru2267
Estra-4,9,11-trien-3-one, 17-α-allyl-17-hydroxy-
drc6246

烯丙孕素生物活性

[ 描述 ]:

Altrenogest(A35957; RU2267)是孕激素,结构与trenbolone相关,能作用于孕激素受体。

[ 相关类别 ]:

信号通路 >> 其他 >> 孕激素受体

研究领域 >> 内分泌

[参考文献]

[1]. Parry-Weeks, L.C. and D.W. Holtan, Effect of altrenogest on pregnancy maintenance in unsynchronized equine embryo recipients. J Reprod Fertil Suppl, 1987. 35: p. 433-8.

[2]. Daels, P.F., et al., Persistence of the luteal phase following ovulation during altrenogest treatment in mares. Theriogenology, 1996. 46(5): p. 799-811.

[相关活性小分子]

烯丙孕素物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
495.6±45.0 °C at 760 mmHg

[ 熔点 ]:
120ºC

[ 分子式 ]:
C₂₁H₂₆O₂

[ 分子量 ]:
310.430

[ 闪点 ]:
210.1±21.3 °C

[ 精确质量 ]:
310.193268

[ PSA ]:
37.30000

[ LogP ]:
3.49

[ 外观性状 ]:
固体;White to Yellow powder to crystal

[ 蒸汽压 ]:
0.0±2.9 mmHg at 25°C

[ 折射率 ]:
1.594

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开存放

烯丙孕素毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KG7745000

CHEMICAL NAME :: Estra-4,9,11-trien-3-one, 17-alpha-allyl-17-hydroxy-

CAS REGISTRY NUMBER :: 850-52-2

LAST UPDATED :: 199509

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C21-H26-O2

MOLECULAR WEIGHT :: 310.47

WISWESSER LINE NOTATION :: L E5 B666 OV AU CU MUTJ E1 FQ F2U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 3 mg/kg

SEX/DURATION :: female 18 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - menstrual cycle changes or disorders

REFERENCE :: THGNBO Theriogenology. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1974- Volume(issue)/page/year: 16,195,1981

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2500 ug/kg

SEX/DURATION :: female 10 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - menstrual cycle changes or disorders

REFERENCE :: JANSAG Journal of Animal Science. (American Soc. of Animal Science, 309 W. Clark St., Champaign, IL 61820) V.1- 1942- Volume(issue)/page/year: 70,1357,1992

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 810 ug/kg

SEX/DURATION :: female 15 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - menstrual cycle changes or disorders Reproductive - Maternal Effects - other effects

REFERENCE :: JRFSAR Journal of Reproduction and Fertility, Supplement. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) No.1- 1966- Volume(issue)/page/year: 32,193,1982

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烯丙孕素安全信息

[ WGK德国 ]:
3.0

[ RTECS号 ]:
KG7745000

[ 海关编码 ]:
2937290090

烯丙孕素海关

[ 海关编码 ]: 2937290090