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L-半胱氨酸乙酯盐酸盐

L-半胱氨酸乙酯盐酸盐用途

L-半胱氨酸乙酯HCl是一种半胱氨酸衍生物[1]。

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L-半胱氨酸乙酯盐酸盐名称

[ CAS 号 ]:
868-59-7

[ 中文名 ]:
L-半胱氨酸乙酯盐酸盐

[ 英文名 ]:
H-Cys-OEt.HCl

[中文别名 ]:

[英文别名 ]:

L-Cysteine Ethyl Ester HCl
EINECS 212-779-6
Cystanin
DL-cysteine ethyl ester hydrochloride
L-Cysteine, ethyl ester, hydrochloride (1:1)
MFCD00012631
Ethyl L-cysteinate hydrochloride (1:1)
E-Cysten
H-CYS-OET
H-Cys-OEt.HCl

L-半胱氨酸乙酯盐酸盐生物活性

[ 描述 ]:

L-半胱氨酸乙酯HCl是一种半胱氨酸衍生物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。

[参考文献]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807.

L-半胱氨酸乙酯盐酸盐物理化学性质

[ 密度 ]:
1.391 g/cm3

[ 沸点 ]:
205.9ºC at 760 mmHg

[ 熔点 ]:
123-125 °C(lit.)

[ 分子式 ]:
C₅H₁₂ClNO₂S

[ 分子量 ]:
185.672

[ 闪点 ]:
78.3ºC

[ 精确质量 ]:
185.027725

[ PSA ]:
91.12000

[ LogP ]:
1.30890

[ 外观性状 ]:
白色结晶粉末

[ 折射率 ]:
-11.5 ° (C=8, 1mol/L HCl)

[ 储存条件 ]:
0-10°C;存放于惰性气体之中;避免湿气 (吸湿),加热

L-半胱氨酸乙酯盐酸盐MSDS

L-半胱氨酸乙酯盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HA1820000

CHEMICAL NAME :: Cysteine, ethyl ester, hydrochloride, L-

CAS REGISTRY NUMBER :: 868-59-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C5-H11-N-O2-S.Cl-H

MOLECULAR WEIGHT :: 185.69

WISWESSER LINE NOTATION :: SH1YZVO2 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,113,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2120 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,113,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 725 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,113,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3470 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,113,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 854 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 20,721,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1550 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,113,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 688 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,113,1982

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L-半胱氨酸乙酯盐酸盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
HA1820000

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L-半胱氨酸乙酯盐酸盐文献

GC-MS analysis of S-nitrosothiols after conversion to S-nitroso-N-acetyl cysteine ethyl ester and in-injector nitrosation of ethyl acetate.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 877(28) , 3442-55, (2009)

S-Nitrosothiols from low-molecular-mass and high-molecular-mass thiols, including glutathione, albumin and hemoglobin, are endogenous potent vasodilators and inhibitors of platelet aggregation. By uti...

Effect of cysteine ethylester hydrochloride (Cystanin) on host defense mechanisms (V): Potentiation of nitroblue tetrazolium reduction and chemiluminescence in macrophages or leukocytes of mice or rats.

Jpn. J. Pharmacol. 53(1) , 57-66, (1990)

L-Cysteine ethylester hydrochloride (Cystanin, ethylcysteine) at doses of 3-30 mg/kg, p.o., potentiated the reduction of nitroblue tetrazolium (NBT) by mouse peritoneal macrophages ex vivo. In in vitr...

Oral L-cysteine ethyl ester (LCEE) reduces amoebic gill disease (AGD) in Atlantic salmon Salmo salar.

Dis. Aquat. Organ. 66(1) , 21-8, (2005)

There is a need for the development of alternative therapeutic treatments for amoebic gill disease (AGD) in Atlantic salmon Salmo salar L. to maintain the sustainability of the Tasmanian Atlantic salm...

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