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L-半胱氨酸甲酯盐酸盐

L-半胱氨酸甲酯盐酸盐用途

Mecysteine盐酸盐是一种镇咳药, 粘痰溶解剂, 用于缓解大量粘痰引起的呼吸困难。

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L-半胱氨酸甲酯盐酸盐名称

[ CAS 号 ]:
18598-63-5

[ 中文名 ]:
L-半胱氨酸甲酯盐酸盐

[ 英文名 ]:
L-Cysteine methyl ester hydrochloride

[中文别名 ]:

[英文别名 ]:

Actiol
H-Cys-OMe·HCl
Mecystein HCl
cysteine methyl ester hydrochloride
methyl L-cysteinate hydrochloride
Acdrile
MFCD00038985
Methyl L-cysteinate hydrochloride (1:1)
EINECS 242-435-0
L-Cysteine, methyl ester, hydrochloride (1:1)

L-半胱氨酸甲酯盐酸盐生物活性

[ 描述 ]:

Mecysteine盐酸盐是一种镇咳药, 粘痰溶解剂, 用于缓解大量粘痰引起的呼吸困难。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[相关活性小分子]

L-半胱氨酸甲酯盐酸盐物理化学性质

[ 沸点 ]:
197.2ºC at 760 mmHg

[ 熔点 ]:
142 °C (dec.)(lit.)

[ 分子式 ]:
C₄H₁₀ClNO₂S

[ 分子量 ]:
171.646

[ 闪点 ]:
73.1ºC

[ 精确质量 ]:
171.012070

[ PSA ]:
91.12000

[ LogP ]:
0.91880

[ 外观性状 ]:
白色粉末

[ 蒸汽压 ]:
0.384mmHg at 25°C

[ 折射率 ]:
-2.5 ° (C=20, MeOH)

[ 储存条件 ]:
存放于惰性气体之中;避免湿气 (吸湿)

L-半胱氨酸甲酯盐酸盐MSDS

详细MSDS(安全技术说明书)

L-半胱氨酸甲酯盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HA2460000

CHEMICAL NAME :: Cysteine, methyl ester, hydrochloride, L-

CAS REGISTRY NUMBER :: 18598-63-5

LAST UPDATED :: 199210

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C4-H9-N-O2-S.Cl-H

MOLECULAR WEIGHT :: 171.66

WISWESSER LINE NOTATION :: SH1YZVO1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,2331,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1340 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,829,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 60 gm/kg/30D-C

TOXIC EFFECTS :: Liver - other changes Kidney, Ureter, Bladder - other changes Blood - normocytic anemia

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 14,1407,1980

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L-半胱氨酸甲酯盐酸盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
HA2460000

[ 海关编码 ]:
2930909090

L-半胱氨酸甲酯盐酸盐上下游产品

L-半胱氨酸甲酯盐酸盐上游产品

L-半胱氨酸甲酯盐酸盐下游产品

L-半胱氨酸甲酯盐酸盐海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

L-半胱氨酸甲酯盐酸盐文献

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The role of hydrogen bonding in the selectivity of L-cysteine methyl ester (CYSM) and L-cysteine ethyl ester (CYSE) for chloride ion.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 61(5) , 845-54, (2005)

The interaction of cysteamine (CY), L-cysteine methyl ester (CYSM), and L-cysteine ethyl ester (CYSE) with nitrate, sulfate, perchlorate, dihydrogen phosphate, and chloride ions was investigated using...

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