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2-氯乙胺盐酸盐

2-氯乙胺盐酸盐用途

-氯乙胺盐酸盐为重要的精细化工原料。在医药工业是可用于合成头孢替安、牛磺酸等。它还是氨基酸、缩二氨酸和核苷酸的衍生试剂。

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2-氯乙胺盐酸盐名称

[ CAS 号 ]:
870-24-6

[ 中文名 ]:
2-氯乙胺盐酸盐

[ 英文名 ]:
2-Chloroethanamine hydrochloride

[中文别名 ]:

[英文别名 ]:

2-Chloropropylamine HCL
β-Chloroethylamine hydrochloride
2-chloroethanamine hydrochloride
2-Chloroethylamine
2-Chloroethylazanium chloride
2-Chloroethylamine h
2-CHLOROETHYLAMINE HCL
MFCD00012887
CHLOROETHYLAMINE HYDROCHLORIDE
2-Chloroethylamine HCl anhyd.

2-氯乙胺盐酸盐物理化学性质

[ 密度 ]:
1.038 g/cm3

[ 沸点 ]:
108.9ºC at 760 mmHg

[ 熔点 ]:
140-150 °C(lit.)

[ 分子式 ]:
C₂H₇Cl₂N

[ 分子量 ]:
115.990

[ 精确质量 ]:
114.995552

[ PSA ]:
26.02000

[ LogP ]:
1.68620

[ 外观性状 ]:
白色至淡米色结晶粉末

[ 折射率 ]:
1.427

[ 储存条件 ]:
库房低温,通风,干燥,与浓碱分开存放

[ 水溶解性 ]:
SOLUBLE

2-氯乙胺盐酸盐MSDS

2-氯乙胺盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KR1800000

CHEMICAL NAME :: Ethylamine, 2-chloro-, hydrochloride

CAS REGISTRY NUMBER :: 870-24-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C2-H6-Cl-N.Cl-H

MOLECULAR WEIGHT :: 116.00

WISWESSER LINE NOTATION :: Z2G &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2204 mg/kg

TOXIC EFFECTS :: Behavioral - ataxia

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 100 umol/L

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,11,1981

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2-氯乙胺盐酸盐安全信息

[ 符号 ]:

GHS05, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314-H341

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ 危险品运输编码 ]:
UN3261

[ WGK德国 ]:
3

[ RTECS号 ]:
KR1800000

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
2921199090

2-氯乙胺盐酸盐合成路线

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2-氯乙胺盐酸盐海关

[ 海关编码 ]: 2921199090

[ 中文概述 ]:
2921199090 其他无环单胺及其衍生物及其盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

2-氯乙胺盐酸盐文献

Synthesis of a carboxamide linked T*T dimer and its incorporation in oligonucleotides.

Nucleic Acids Res. 21 , 5179, (1993)

The condensation of 5'-O-protected 3'-O-(2-aminoethyl)thymidine with 1,2-dideoxy-1-thyminyl-beta-D-erythro-pentofuranuronic acid gives a T*T dimer with * representing a 3'-OCH2CH2NHC(O)-4' linkage con...

In the search for new anticancer drugs. XXIV: Synthesis and anticancer activity of amino acids and dipeptides containing the 2-chloroethyl- and [N'-(2-chloroethyl)-N'-nitroso]-aminocarbonyl groups.

J. Pharm. Sci. 82 , 1, (1993)

A series of L,L- (42, 44, 46, and 60) and D,D- (43, 45, 47, and 61) dipeptide derivatives composed of phenylglycine, phenylalanine, homophenylalanine, and valine and containing a 2-chloroethylamino gr...

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