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9-氨基吖啶

9-氨基吖啶用途

9-Aminoacridine是一种高度荧光染料, 临床上用作局部消毒剂, 实验用作一种诱变剂, 细胞内pH指示剂。

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9-氨基吖啶名称

[ CAS 号 ]:
90-45-9

[ 中文名 ]:
9-氨基吖啶

[ 英文名 ]:
9-Aminoacridine

[中文别名 ]:

[英文别名 ]:

MFCD00037839
EINECS 201-995-6
9-Aminoacridine
9-aminoacridiniun

9-氨基吖啶生物活性

[ 描述 ]:

9-Aminoacridine是一种高度荧光染料, 临床上用作局部消毒剂, 实验用作一种诱变剂, 细胞内pH指示剂。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

染料试剂

研究领域 >> 其他

[相关活性小分子]

9-氨基吖啶物理化学性质

[ 密度 ]:
1.268g/cm3

[ 沸点 ]:
413.5ºC at 760 mmHg

[ 熔点 ]:
241ºC

[ 分子式 ]:
C₁₃H₁₀N₂

[ 分子量 ]:
194.23200

[ 闪点 ]:
233.2ºC

[ 精确质量 ]:
194.08400

[ PSA ]:
38.91000

[ LogP ]:
3.55140

[ 外观性状 ]:
黄色晶体或粉末

[ 折射率 ]:
1.78

[ 储存条件 ]:
库房通风低温干燥

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
ethanol: hazy

9-氨基吖啶MSDS

详细MSDS(安全技术说明书)

9-氨基吖啶毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AR7300000

CHEMICAL NAME :: Acridine, 9-amino-

CAS REGISTRY NUMBER :: 90-45-9

BEILSTEIN REFERENCE NO. :: 0141171

LAST UPDATED :: 199710

DATA ITEMS CITED :: 32

MOLECULAR FORMULA :: C13-H10-N2

MOLECULAR WEIGHT :: 194.25

WISWESSER LINE NOTATION :: T C666 BNJ IZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 68 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory stimulation

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: Specific locus test

TYPE OF TEST :: Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 10 mmol/L

REFERENCE :: CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 44,53,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - B0081 No. of Facilities: 75 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 299 (estimated)

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9-氨基吖啶安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
2811

[ WGK德国 ]:
3

[ RTECS号 ]:
AR7300000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

9-氨基吖啶制备

由9-氯吖啶得到。N-苯氨茴酸和五氯化磷一起加热可得到9-氯吖啶。

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9-氨基吖啶文献

Genotoxicity testing of esterified propoxylated glycerol (EPG).

Regul Toxicol Pharmacol 70 Suppl 2 , S131-42, (2014)

Four versions of esterified propoxylated glycerols (EPGs) were evaluated for potential genotoxicity using a range of in vitro and in vivo assays. H-EPG-05 HR/SO 9:1, H-EPG-05 soyate, and H-EPG-14 soya...

Mutagenicity and DNA-damaging potential of clenbuterol and its metabolite 4-amino-3,5-dichlorobenzoic acid in vitro.

Food Chem. Toxicol. 77 , 82-92, (2015)

The aim of this study was to evaluate in vitro toxicity of clenbuterol and its metabolite 4-amino-3,5-dichlorobenzoic acid. Cytotoxicity and pro-oxidative effect of both compounds were studied on huma...

Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction.

J. Lipid Res. 55(11) , 2354-69, (2014)

Mammalian kidneys are rich in sulfatides. Papillary sulfatides, especially, contribute to renal adaptation to chronic metabolic acidosis. Due to differences in their cer-amide (Cer) anchors, the struc...

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9-氨基吖啶

9-氨基吖啶用途

9-氨基吖啶名称

9-氨基吖啶生物活性

9-氨基吖啶物理化学性质

9-氨基吖啶MSDS

详细MSDS(安全技术说明书)

9-氨基吖啶毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

9-氨基吖啶安全信息

9-氨基吖啶制备

9-氨基吖啶文献

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