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胰凝乳蛋白酶抑制剂

胰凝乳蛋白酶抑制剂用途

凝乳蛋白酶是一种有效的组织蛋白酶G抑制剂。凝乳酶抑素与其他胃蛋白酶抑制剂联合使用可抑制真菌生长。凝乳蛋白酶可用于急性肺损伤和胰腺炎的研究[1]。

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胰凝乳蛋白酶抑制剂名称

[ CAS 号 ]:
9076-44-2

[ 中文名 ]:
抑糜朊酶素

[ 英文名 ]:
chymostatin

[中文别名 ]:

胰凝乳蛋白酶抑制剂

[英文别名 ]:

MFCD00071059
CHYMOSTATIN (MICROBIAL PRODUCT)
Chymostatin
CHYMOSTATIN, 5 MG
CHYMOSTATIN (25 MG )
CHYMOSTATIN (ACTINOMYCETES)

胰凝乳蛋白酶抑制剂生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 炎症/免疫

信号通路 >> 代谢酶/蛋白酶 >> 组织蛋白酶

[参考文献]

[1]. Chen Yang, et al. Protective Effects of Chymostatin on Paraquat-Induced Acute Lung Injury in Mice. Inflammation

胰凝乳蛋白酶抑制剂物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 熔点 ]:
276-278℃

[ 分子式 ]:
C₃₁H₄₁N₇O₆

[ 分子量 ]:
607.701

[ 精确质量 ]:
607.311829

[ PSA ]:
201.61000

[ LogP ]:
4.00

[ 折射率 ]:
1.640

[ 储存条件 ]:
−20°C

[ 水溶解性 ]:
DMSO: 10 mM Stock solutions stable for months at −20 °C.

胰凝乳蛋白酶抑制剂安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
22-24/25-36-26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
GC3047700

胰凝乳蛋白酶抑制剂文献

Enabling Low Cost Biopharmaceuticals: A Systematic Approach to Delete Proteases from a Well-Known Protein Production Host Trichoderma reesei.

PLoS ONE 10 , e0134723, (2015)

The filamentous fungus Trichoderma reesei has tremendous capability to secrete proteins. Therefore, it would be an excellent host for producing high levels of therapeutic proteins at low cost. Develop...

Estrogen inhibits mast cell chymase release to prevent pressure overload-induced adverse cardiac remodeling.

Hypertension 65(2) , 328-34, (2015)

Estrogen regulation of myocardial chymase and chymase effects on cardiac remodeling are unknown. To test the hypothesis that estrogen prevents pressure overload-induced adverse cardiac remodeling by i...

Primacy of angiotensin converting enzyme in angiotensin-(1-12) metabolism.

Am. J. Physiol. Heart Circ. Physiol. 305(5) , H644-50, (2013)

Angiotensin-(1-12) [ANG-(1-12)], a new member of the renin-angiotensin system, is recognized as a renin independent precursor for ANG II. However, the processing of ANG-(1-12) in the circulation in vi...

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