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DL-丙交酯

DL-丙交酯用途

主要用于医药方面。

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DL-丙交酯名称

[ CAS 号 ]:
95-96-5

[ 中文名 ]:
3,6-二甲基-1,4-二氧杂环己烷-2,5-二酮

[ 英文名 ]:
lactide

[中文别名 ]:

[英文别名 ]:

L-(-)-Dilactide
(3S)-cis-3,6-Dimethyl-1,4-dioxane-2,5-dione
L-(-)-Lactide
3,6-Dimethyl-1,4-dioxane-2,5-dione
1,4-Dioxane-2,5-dione, 3,6-dimethyl-
EINECS 202-468-3
UNII:7EH08MWO6M
L-Lactide
MFCD00011685
DL-Lactide

DL-丙交酯物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
285.5±15.0 °C at 760 mmHg

[ 熔点 ]:
116-119ºC

[ 分子式 ]:
C₆H₈O₄

[ 分子量 ]:
144.125

[ 闪点 ]:
150.6±18.8 °C

[ 精确质量 ]:
144.042252

[ PSA ]:
52.60000

[ LogP ]:
-1.45

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.429

[ 储存条件 ]:
2~8℃

DL-丙交酯MSDS

DL-丙交酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JH1100000

CHEMICAL NAME :: 1,4-Dioxane-2,5-dione, 3,6-dimethyl-

CAS REGISTRY NUMBER :: 95-96-5

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H8-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 35 gm/kg/2W-I

TOXIC EFFECTS :: Gastrointestinal - changes in structure or function of esophagus Gastrointestinal - ulceration or bleeding from stomach Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 36(1, Pt 2),274,1997

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 9100 mg/kg/13W-I

TOXIC EFFECTS :: Gastrointestinal - ulceration or bleeding from stomach

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 36(1, Pt 2),274,1997

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DL-丙交酯安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3.0

[ RTECS号 ]:
JH1100000

[ 海关编码 ]:
2934999090

DL-丙交酯合成路线

DL-丙交酯上下游产品

DL-丙交酯上游产品

DL-丙交酯下游产品

DL-丙交酯制备

以D ,L - 乳酸为原料,在催化剂存在下通过脱水环化合成D ,L - 丙交酯。用重结晶法对粗产物进行纯化,制备出高产率、高纯度的D ,L - 丙交酯。

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DL-丙交酯海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

DL-丙交酯文献

Magnesium amino-bis(phenolato) complexes for the ring-opening polymerization of rac-lactide.

Dalton Trans. 44 , 12365-75, (2015)

Magnesium compounds of tetradentate amino-bis(phenolato) ligands, Mg[L1] (1) and Mg[L2] (2) (where [L1] = 2-pyridyl-N,N-bis(2-methylene-4-methoxy-6-tert-butylphenolato), and [L2] = dimethylaminoethyla...

The influence of spray-drying parameters on phase behavior, drug distribution, and in vitro release of injectable microspheres for sustained release.

J. Pharm. Sci. 104(4) , 1451-60, (2015)

For ternary solid dispersions, it is indispensable to characterize their structure, phase behavior, and the spatial distribution of the dispersed drug as this might influence the release profile and/o...

Microfluidic Synthesis of Hybrid Nanoparticles with Controlled Lipid Layers: Understanding Flexibility-Regulated Cell-Nanoparticle Interaction.

ACS Nano 9 , 9912-21, (2015)

The functionalized lipid shell of hybrid nanoparticles plays an important role for improving their biocompatibility and in vivo stability. Yet few efforts have been made to critically examine the shel...

更多文献

DL-丙交酯

DL-丙交酯用途

DL-丙交酯名称

DL-丙交酯物理化学性质

DL-丙交酯MSDS

详细MSDS(安全技术说明书)

DL-丙交酯毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

DL-丙交酯安全信息

DL-丙交酯合成路线

详细合成路线

DL-丙交酯上下游产品

DL-丙交酯上游产品

DL-丙交酯下游产品

DL-丙交酯制备

DL-丙交酯海关

DL-丙交酯文献

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