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4-BOC-氨基哌啶

4-BOC-氨基哌啶结构式
4-BOC-氨基哌啶结构式
品牌特惠专场
常用名 4-BOC-氨基哌啶 英文名 4-(N-BOC-AMINO)PIPERIDINE
CAS号 73874-95-0 分子量 200.28
密度 1.0±0.1 g/cm3 沸点 304.8±31.0 °C at 760 mmHg
分子式 C10H20N2O2 熔点 162-166 °C(lit.)
MSDS 中文版 美版 闪点 138.2±24.8 °C
符号 GHS07
GHS07
信号词 Warning

Discovery of a piperidine-4-carboxamide CCR5 antagonist (TAK-220) with highly potent Anti-HIV-1 activity.

J. Med. Chem. 49 , 2784, (2006)

We incorporated various polar groups into previously described piperidine-4-carboxamide CCR5 antagonists to improve their metabolic stability in human hepatic microsomes. Introducing a carbamoyl group into the phenyl ring of the 4-benzylpiperidine moiety affo...

Synthesis of potent oxindole CDK2 inhibitors.

Bioorg. Med. Chem. 11 , 1873-1881, (2003)

A series of oxindole CDK2 inhibitors was synthesized. These novel analogues have a saturated monosubstituted cyclic moiety at their C-4 position that mimics the ribofuranoside of ATP. This substitution afforded agents with increased potency relative to the pa...

Poly (2-isopropyl-2-oxazoline)-poly (L-glutamate) block copolymers through ammonium-mediated NCA polymerization. Meyer M and Schlaad H.

Macromolecules 39(11) , 3967-3970, (2006)