邻氨基苯甲酸

一般危化品
邻氨基苯甲酸结构式
邻氨基苯甲酸结构式
常用名 邻氨基苯甲酸 英文名 Anthranilic acid
CAS号 118-92-3 分子量 137.136
密度 1.3±0.1 g/cm3 沸点 311.9±25.0 °C at 760 mmHg
分子式 C7H7NO2 熔点 144-148 °C(lit.)
MSDS 中文版 美版 闪点 142.4±23.2 °C
符号 GHS07
GHS07
信号词 Warning

Toxicological assessment and management options for boat pressure-washing wastewater.

Ecotoxicol. Environ. Saf. 114 , 164-70, (2015)

Boats are washed periodically for maintenance in order to remove biofoulants from hulls, which results in the generation of wastewater. This study aimed at evaluating the cyto/genotoxic and mutagenic properties of wastewater produced by pressure washing of bo...

Development of a quantitative mass spectrometry multi-attribute method for characterization, quality control testing and disposition of biologics.

MAbs 7 , 881-90, (2015)

Regulatory agencies have recently recommended a Quality by Design (QbD) approach for the manufacturing of therapeutic molecules. A QbD strategy requires deep understanding at the molecular level of the attributes that are crucial for safety and efficacy and f...

Coformer screening using thermal analysis based on binary phase diagrams.

Pharm. Res. 31(8) , 1946-57, (2014)

The advent of cocrystals has demonstrated a growing need for efficient and comprehensive coformer screening in search of better development forms, including salt forms. Here, we investigated a coformer screening system for salts and cocrystals based on binary...

Stable isotopic labeling-based quantitative targeted glycomics (i-QTaG).

Biotechnol. Prog. 31 , 840-8, (2015)

Mass spectrometry (MS) analysis combined with stable isotopic labeling is a promising method for the relative quantification of aberrant glycosylation in diseases and disorders. We developed a stable isotopic labeling-based quantitative targeted glycomics (i-...

Comparative studies of N-glycans and glycosaminoglycans present in SIRC (Statens Seruminstitut rabbit cornea) cells and corneal epithelial cells from rabbit eyes.

Curr. Eye Res. 39(7) , 686-94, (2014)

We compared cultured Statens Seruminstitut rabbit cornea (SIRC) cells and corneal epithelial cells from rabbit eyes by analyzing their N-glycans and glycosaminoglycans (GAGs). This work is a fundamental study on the efficacy of using cultured cells instead of...

Discrimination of isobaric Leu/Ile residues by MALDI in-source decay mass spectrometry.

J. Am. Soc. Mass Spectrom. 24(2) , 297-300, (2013)

MALDI in-source decay (ISD) has been used for top-down sequencing of proteins. The use of the matrix 1,5-diaminonapthalene (1,5-DAN) gave abundant w ions, which are formed from the unimolecular dissociation of z• radical fragments via α cleavage reaction and ...

Slow Off-rates and Strong Product Binding Are Required for Processivity and Efficient Degradation of Recalcitrant Chitin by Family 18 Chitinases.

J. Biol. Chem. 290 , 29074-85, (2015)

Processive glycoside hydrolases are the key components of enzymatic machineries that decompose recalcitrant polysaccharides, such as chitin and cellulose. The intrinsic processivity (P(Intr)) of cellulases has been shown to be governed by the rate constant of...

Systemic tryptophan and kynurenine catabolite levels relate to severity of rhinovirus-induced asthma exacerbation: a prospective study with a parallel-group design.

Thorax 68(12) , 1122-30, (2013)

Patients with allergic asthma have exacerbations which are frequently caused by rhinovirus infection. The antiviral tryptophan-catabolising enzyme indoleamine 2,3-dioxygenase (IDO) is induced by interferon-γ and suppressed by Th2 mediators interleukin (IL)-4 ...

Vitamin B1 deficiency inhibits the increased conversion of tryptophan to nicotinamide in severe food-restricted rats.

Biosci. Biotechnol. Biochem. 79(1) , 103-8, (2015)

The conversion of tryptophan (Trp) → nicotinamide (Nam) is an important pathway for supplying vitamin niacin. We reported the following two phenomena: (1) severe food restriction led to an increase in the Trp → Nam conversion compared with free-access control...

Time-dependent effects of L-tryptophan administration on urinary excretion of L-tryptophan metabolites.

J. Nutr. Sci. Vitaminol. 60(4) , 255-60, (2014)

We have previously reported that dietary supplementation with up to 5.0 g/d of L-tryptophan (L-Trp) for 21 d has no adverse effects, judging from the levels of general blood variables, in healthy women. We performed a randomized, double-blind, placebo-control...