尼可地尔
尼可地尔结构式
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常用名 | 尼可地尔 | 英文名 | Nicorandil |
|---|---|---|---|---|
| CAS号 | 65141-46-0 | 分子量 | 211.175 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 456.7±25.0 °C at 760 mmHg | |
| 分子式 | C8H9N3O4 | 熔点 | 92ºC | |
| MSDS | 中文版 美版 | 闪点 | 230.0±23.2 °C | |
| 符号 |
GHS05, GHS07 |
信号词 | Danger |
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Leg ulcers associated with nicorandil are possibly underdiagnosed.
Clin. Exp. Dermatol. 38(2) , 193-4, (2013)
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Treating stable angina - is there a NICE way towards an international consensus?
Int. J. Clin. Pract. 66(7) , 614-8, (2012)
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Peristomal ulceration caused by nicorandil.
Clin. Exp. Dermatol. 34(1) , 87-8, (2009)
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Nicorandil-associated perianal ulceration: a case series of 10 patients.
Br. J. Dermatol. 154(1) , 199-200, (2006)
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Nicorandil-associated perianal ulceration with prominent elastophagocytosis and flexural ulceration.
Br. J. Dermatol. 152(6) , 1360-1, (2005)
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Combination of ACE inhibitor with nicorandil provides further protection in chronic kidney disease.
Am. J. Physiol. Renal Physiol. 307(12) , F1313-22, (2014) An inhibition in the renin-angiotensin system (RAS) is one of the most widely used therapies to treat chronic kidney disease. However, its effect is occasionally not sufficient and additional treatments may be required. Recently, we reported that nicorandil e... |
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Nicorandil associated anal ulcers: an estimate of incidence.
Ann. R. Coll. Surg. Engl. 94(3) , 170-2, (2012) Nicorandil is a commonly prescribed antianginal medication that has been found to be associated with painful anal ulceration. The incidence of this complication is unknown. We have used the best data available to us to make an estimate of this figure in a hea... |
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Blunted proarrhythmic effect of nicorandil in a Langendorff-perfused phase-2 myocardial infarction rabbit model.
Pacing Clin. Electrophysiol. 36(2) , 142-51, (2013) Nicorandil (a K(ATP) opener) administration is reported to reduce ventricular arrhythmias 4.8 ± 2.2 hours after myocardial infarction (MI). The electrophysiological changes and the effects on dynamic factors and dynamically induced spatially discordant altern... |
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Should nicorandil infusion be adapted in dialysis-dependent patients undergoing continuous renal replacement therapy after cardiac surgery?
Artif. Organs 37(3) , 319-22, (2013) In this report, we studied whether plasma concentration of nicorandil is maintained effectively and safely in dialysis-dependent patients with stage 5 chronic kidney disease (CKD5D) undergoing continuous renal replacement therapy (CRRT). Participants consiste... |
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Nicorandil-associated ulcerations.
Eur. J. Gastroenterol. Hepatol. 19(5) , 395-8, (2007) This leading article refers to the paper by Abdelrazeq AS, Owen C, Smith L, McAdam JG, Pearson HJ, Leveson SH. Nicorandil-associated para-stomal ulceration: case series Eur J Gastroenterol Hepatol 2006; 18:1293-1295. We apologise to all concerned for the diss... |