弹性蛋白酶,来源猪胰腺
弹性蛋白酶,来源猪胰腺结构式
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常用名 | 弹性蛋白酶,来源猪胰腺 | 英文名 | Elastase from porcine pancreas |
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| CAS号 | 39445-21-1 | 分子量 | 474.93574 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C20H31N4O7Cl | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07, GHS08 |
信号词 | Danger, Warning |
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Targeting latent TGFβ release in muscular dystrophy.
Sci. Transl. Med. 6(259) , 259ra144, (2014) Latent transforming growth factor-β (TGFβ) binding proteins (LTBPs) bind to inactive TGFβ in the extracellular matrix. In mice, muscular dystrophy symptoms are intensified by a genetic polymorphism that changes the hinge region of LTBP, leading to increased p... |
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Can we predict postoperative pancreatic leakage after pancreaticoduodenectomy using preoperative fecal elastase-1 level?
J. Clin. Lab Anal. 27(5) , 379-83, (2013) The measurement of fecal elastas-1 in stools is a sensitive and relatively inexpensive noninvasive test. The aim of this study was to study fecal elastase levels in patients who develop pancreatic leakage after pancreaticoduodenectomy (PD) to determine if fec... |
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Collagenase mRNA Overexpression and Decreased Extracellular Matrix Components Are Early Events in the Pathogenesis of Emphysema.
PLoS ONE 10 , e0129590, (2015) To describe the progression of parenchymal remodeling and metalloproteinases gene expression in earlier stages of emphysema, mice received porcine pancreatic elastase (PPE) instillation and Control groups received saline solution. After PPE instillation (1, 3... |
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Tumor necrosis factor-like weak inducer of apoptosis or Fn14 deficiency reduce elastase perfusion-induced aortic abdominal aneurysm in mice.
J. Am. Heart Assoc. 3(4) , doi:10.1161/JAHA.113.000723, (2014) Abdominal aortic aneurysm (AAA) involves leukocyte recruitment, inflammatory cytokine production, vascular cell apoptosis, neovascularization, and vascular remodeling, all of which contribute to aortic dilatation. Tumor necrosis factor-like weak inducer of ap... |
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[Hydrolytic activity of microorganisms of the Dead Sea coastal ecosystems].
Mikrobiol. Z. 76(1) , 16-20, (2014) All strains tested are characterized by proteolytic (caseinolytic) activity, while elastase one was revealed only in two Gracilibacillus strains 6T2 and 7Tl. The activity was high enough (23.1 and 34.7 E/Ml, respectively). These values are at the level of bac... |
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Imatinib attenuates inflammation and vascular leak in a clinically relevant two-hit model of acute lung injury.
Am. J. Physiol. Lung Cell. Mol. Physiol. 309 , L1294-304, (2015) Acute lung injury/acute respiratory distress syndrome (ALI/ARDS), an illness characterized by life-threatening vascular leak, is a significant cause of morbidity and mortality in critically ill patients. Recent preclinical studies and clinical observations ha... |
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Differential and opposing effects of imatinib on LPS- and ventilator-induced lung injury.
Am. J. Physiol. Lung Cell. Mol. Physiol. 308(3) , L259-69, (2015) Endothelial dysfunction underlies the pathophysiology of vascular disorders such as acute lung injury (ALI) syndromes. Recent work has identified the Abl family kinases (c-Abl and Arg) as important regulators of endothelial cell (EC) barrier function and sugg... |
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Clinically relevant cell sources for TMJ disc engineering.
J. Dent. Res. 87 , 548-52, (2010) Tissue-engineering of the temporomandibular joint (TMJ) disc aims to provide patients with TMJ disorders an option to replace diseased tissue with autologous, functional tissue. This study examined clinically relevant cell sources by comparing costal chondroc... |
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Antioxidant Vitamin C attenuates experimental abdominal aortic aneurysm development in an elastase-induced rat model
J. Surg. Res. 188(1) , 316-25, (2014) Background We investigated the hypothesis that an antioxidant, Vitamin C, could attenuate abdominal aortic aneurysm (AAA) development in a rat model. |
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A spider-derived Kunitz-type serine protease inhibitor that acts as a plasmin inhibitor and an elastase inhibitor.
PLoS ONE 8(1) , e53343, (2013) Kunitz-type serine protease inhibitors are involved in various physiological processes, such as ion channel blocking, blood coagulation, fibrinolysis, and inflammation. While spider-derived Kunitz-type proteins show activity in trypsin or chymotrypsin inhibit... |