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二氯乙基醚

一般危化品
二氯乙基醚结构式
二氯乙基醚结构式
常用名 二氯乙基醚 英文名 Bis(chloroethyl) ether
CAS号 111-44-4 分子量 143.012
密度 1.2±0.1 g/cm3 沸点 178.7±0.0 °C at 760 mmHg
分子式 C4H8Cl2O 熔点 −47 °C(lit.)
MSDS 中文版 美版 闪点 55.0±0.0 °C
符号 GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
信号词 Danger

Carcinogenicity tests of certain environmental and industrial chemicals.

J. Natl. Cancer Inst. 67(1) , 75-88, (1981)

Fourteen chemicals of varied uses were tested for carcinogenicity by oral administration in male and female Charles River CD rats. Under the conditions of the tests, propane sultone, propylene imine, and ethylenethiourea, in addition to the positive control N...

Thiodiglycolic acid: a major metabolite of bis(2-chloroethyl)ether.

Toxicol. Appl. Pharmacol. 47(1) , 23-34, (1979)

Male rats were given a single oral dose (40 mg/kg) of bis(2-chloroethyl)ether (BCEE). Less than 2% of the dose was recovered from the expired air as the unaltered parent compound during an 8-hr collection period. Urine samples representing 48 hr of collection...

Bis(2-chloroethyl)ether.

IARC Monogr. Eval. Carcinog. Risks Hum. 71 Pt 3 , 1265-9, (1999)

[Medical topics: bischloromethyl ether and lung cancer].

Kango. 37(14) , 82, (1985)

Treatment of persistent organic compounds by integrated advanced oxidation processes and sequential batch reactor

Water Res. 43(16) , 3910-21, (2009)

The objective of this study was to evaluate the extent of improvement in the biodegradability of persistent organic compounds by pre-oxidation by using Sequential Batch Reactors (SBRs). Dichlorodiethyl ether (DCDE), a non-biodegradable compound, was used as a...

Chemical mutagenesis testing in Drosophila. IX. Results of 50 coded compounds tested for the National Toxicology Program.

Environ. Mol. Mutagen. 23(1) , 51-63, (1994)

Fifty chemicals were tested for mutagenic activity in post-meiotic and meiotic germ cells of male Drosophila melanogaster using the sex-linked recessive lethal (SLRL) assay. As in the previous studies in this series, feeding was chosen as the first route of a...

Evidence of chloroethylene oxide being the reactive metabolite of vinyl chloride towards DNA: comparative studies with 2,2'-dichlorodiethylether.

Carcinogenesis 4(11) , 1483-6, (1983)

The roles of chloroethylene oxide (CEO) and chloroacetaldehyde (CAA) in carcinogenicity of vinyl chloride (VC) have been studied by comparing biological effects of VC exposure with those of 2,2'-dichlorodiethylether (bis(chloroethyl)ether, BCEE) as a metaboli...

Biodegradation of bis(2-chloroethyl) ether by Xanthobacter sp. strain ENV481.

Appl. Environ. Microbiol. 73(21) , 6870-5, (2007)

Degradation of bis(2-chloroethyl) ether (BCEE) was observed to occur in two bacterial strains. Strain ENV481, a Xanthobacter sp. strain, was isolated by enrichment culturing of samples from a Superfund site located in the northeastern United States. The strai...

Surface catalyzed Fenton treatment of bis(2-chloroethyl) ether and bis(2-chloroethoxy) methane.

Chemosphere 70(8) , 1390-8, (2008)

This study examined the feasibility of using surface catalyzed Fenton treatment to remediate soil and groundwater contaminated by the chlorinated ethers, bis(2-chloroethyl) ether (BCEE) and bis(2-chloroethoxy) methane (BCEM). Parameters that affect the contam...

Metabolism of bis(2-chloroethyl)ether and bis(2-chloroisopropyl)ether in the rat.

Arch. Environ. Contam. Toxicol. 11(2) , 173-83, (1982)

Male rats were given single peroral doses of bis(1-14C-2-chloroethyl)ether ([1-14C]BCEE) (40 mg/kg) and of bis(1-14C-2-chloroisopropyl)ether ([1-14C]BCIE) (90 mg/kg). Excretion of 14CO2 and urinary 14C was followed for 48 hr. The time required to eliminate on...