盐酸多巴胺
盐酸多巴胺结构式
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常用名 | 盐酸多巴胺 | 英文名 | Dopamine hydrochloride |
|---|---|---|---|---|
| CAS号 | 62-31-7 | 分子量 | 189.639 | |
| 密度 | N/A | 沸点 | 337.7ºC at 760 mmHg | |
| 分子式 | C8H12ClNO2 | 熔点 | 248-250 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 11 °C | |
| 符号 |
GHS07, GHS09 |
信号词 | Warning |
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'Dopamine-first' mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile.
FEBS J. 282(6) , 1137-51, (2015) Norcoclaurine synthase (NCS) (EC 4.2.1.78) catalyzes the Pictet-Spengler condensation of dopamine and an aldehyde, forming a substituted (S)-tetrahydroisoquinoline, a pharmaceutically important moiety. This unique activity has led to NCS being used for both i... |
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Permeation of Dopamine Sulfate through the Blood-Brain Barrier.
PLoS ONE 10 , e0133904, (2015) Dopamine sulfate (DA-3- and DA-4-S) have been determined in the human brain, but it is unclear whether they are locally formed in the central nervous system (CNS), or transported into the CNS from peripheral sources. In the current study, permeation of the bl... |
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Increasing the Collision Rate of Particle Impact Electroanalysis with Magnetically Guided Pt-Decorated Iron Oxide Nanoparticles.
ACS Nano 9 , 7583-95, (2015) An integrated microfluidic/magnetophoretic methodology was developed for improving signal response time and detection limits for the chronoamperometric observation of discrete nanoparticle/electrode interactions by electrocatalytic amplification. The strategy... |
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Force nanoscopy of hydrophobic interactions in the fungal pathogen Candida glabrata.
ACS Nano 9(2) , 1648-55, (2015) Candida glabrata is an opportunistic human fungal pathogen which binds to surfaces mainly through the Epa family of cell adhesion proteins. While some Epa proteins mediate specific lectin-like interactions with human epithelial cells, others promote adhesion ... |
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A simple method for patterning poly(dimethylsiloxane) barriers in paper using contact-printing with low-cost rubber stamps.
Anal. Chim. Acta 858 , 82-90, (2015) This paper presents a simple and low-cost method for patterning poly(dimethylsiloxane) (PDMS) barriers in porous support such as paper for the construction of flexible microfluidic paper-based analytical devices (μPADs). The fabrication method consisted of co... |
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Novel molecularly imprinted stir bar sorptive extraction based on an 8-electrode array for preconcentration of trace exogenous estrogens in meat.
Anal. Chim. Acta 853 , 342-50, (2014) A novel 8-electrode array as stir bar was designed for selective extraction of trace level exogenous estrogens from food samples, followed by liquid desorption and HPLC-photodiode array detection. The array consisted of 8 screen-printed electrodes and each el... |
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Rho kinase inhibition by fasudil in the striatal 6-hydroxydopamine lesion mouse model of Parkinson disease.
J. Neuropathol. Exp. Neurol. 73(8) , 770-9, (2014) Chronic degeneration of nigrostriatal projections, followed by nigral dopaminergic cell death, is a key feature of Parkinson disease (PD). This study examines the neuroprotective potential of the rho kinase inhibitor fasudil in the 6-hydroxydopamine (6-OHDA) ... |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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Control of heterogeneous nucleation and growth kinetics of dopamine-melanin by altering substrate chemistry.
Langmuir 31(11) , 3451-8, (2015) Dopamine-melanin (DM or "polydopamine") can be deposited on virtually any substrate from solution through autoxidation of dopamine. The versatility of this process has allowed surface-mediated assembly of DM for a wide variety of functional coatings. Here we ... |
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Hydrophilic Nb⁵⁺-immobilized magnetic core-shell microsphere--A novel immobilized metal ion affinity chromatography material for highly selective enrichment of phosphopeptides.
Anal. Chim. Acta 880 , 67-76, (2015) Rapid and selective enrichment of phosphopeptides from complex biological samples is essential and challenging in phosphorylated proteomics. In this work, for the first time, niobium ions were directly immobilized on the surface of polydopamine-coated magneti... |