甲酸

一般危化品
甲酸结构式
甲酸结构式
常用名 甲酸 英文名 Formic Acid
CAS号 64-18-6 分子量 46.025
密度 1.2±0.1 g/cm3 沸点 100.6±9.0 °C at 760 mmHg
分子式 CH2O2 熔点 8.2-8.4 °C(lit.)
MSDS 中文版 美版 闪点 29.9±13.4 °C
符号 GHS02 GHS05 GHS06
GHS02, GHS05, GHS06
信号词 Danger

Neuroprotective effect of modified Chungsimyeolda-tang, a traditional Korean herbal formula, via autophagy induction in models of Parkinson's disease.

J. Ethnopharmacol. 159 , 93-101, (2014)

Previous studies in our laboratory revealed the neuroprotective effect of modified Yeoldahanso-tang (MYH) in models of Parkinson׳s disease (PD). In this study, we investigated another traditional Korean herbal formula, modified Chungsimyeolda-tang (termed DG)...

Biomolecular imaging with a C60-SIMS/MALDI dual ion source hybrid mass spectrometer: instrumentation, matrix enhancement, and single cell analysis.

J. Am. Soc. Mass Spectrom. 25(11) , 1897-907, (2014)

We describe a hybrid MALDI/C(60)-SIMS Q-TOF mass spectrometer and corresponding sample preparation protocols to image intact biomolecules and their fragments in mammalian spinal cord, individual invertebrate neurons, and cultured neuronal networks. A lateral ...

Methionine oxidation accelerates the aggregation and enhances the neurotoxicity of the D178N variant of the human prion protein.

Biochim. Biophys. Acta 1842(12 Pt A) , 2345-56, (2014)

The D178N mutation of the prion protein (PrP) results in the hereditary prion disease fatal familial insomnia (FFI). Little is known regarding the effects of methionine oxidation on the pathogenesis of D178N-associated FFI. In the present study, we found that...

Quantification of furanic derivatives in fortified wines by a highly sensitive and ultrafast analytical strategy based on digitally controlled microextraction by packed sorbent combined with ultrahigh pressure liquid chromatography.

J. Chromatogr. A. 1381 , 54-63, (2015)

An improved, reliable and powerful analytical strategy based on digitally controlled microextraction by packed sorbent (MEPS) combined with ultrahigh pressure liquid chromatography (UHPLC) was validated for the simultaneous identification and quantification o...

Silencing urease: a key evolutionary step that facilitated the adaptation of Yersinia pestis to the flea-borne transmission route.

Proc. Natl. Acad. Sci. U. S. A. 111(52) , 18709-14, (2014)

The arthropod-borne transmission route of Yersinia pestis, the bacterial agent of plague, is a recent evolutionary adaptation. Yersinia pseudotuberculosis, the closely related food-and water-borne enteric species from which Y. pestis diverged less than 6,400 ...

To the novel paradigm of proteome-based cell therapy of tumors: through comparative proteome mapping of tumor stem cells and tissue-specific stem cells of humans.

Cell. Transplant. 23 Suppl 1 , S151-70, (2014)

We performed proteome mapping (PM), cataloging, and bioinformation analysis of protein lysates of human neural (CD133(+)) progenitor and stem cells (NPSCs) isolated from the olfactory sheath of a nose, multipotent mesenchymal (CD29(+), CD44(+), CD73(+), CD90(...

Isoforms of Hsp70-binding human LDL in adult Schistosoma mansoni worms.

Parasitol. Res. 114(3) , 1145-52, (2015)

Schistosoma mansoni is one of the most common parasites infecting humans. They are well adapted to the host, and this parasite's longevity is a consequence of effective escape from the host immune system. In the blood circulation, lipoproteins not only help t...

Buprenorphine decreases the CCL2-mediated chemotactic response of monocytes.

J. Immunol. 194(7) , 3246-58, (2015)

Despite successful combined antiretroviral therapy, ∼ 60% of HIV-infected people exhibit HIV-associated neurocognitive disorders (HAND). CCL2 is elevated in the CNS of infected people with HAND and mediates monocyte influx into the CNS, which is critical in n...

TiO2 immobilized on Manihot carbon: optimal preparation and evaluation of its activity in the decomposition of indigo carmine.

Int. J. Mol. Sci. 16(1) , 1590-612, (2015)

Applications of carbon-TiO2 materials have attracted attention in nanotechnology due to their synergic effects. We report the immobilization of TiO2 on carbon prepared from residues of the plant Manihot, commercial TiO2 and glycerol. The objective was to obta...

Evidence of histidine and aspartic acid phosphorylation in human prostate cancer cells.

Naunyn Schmiedebergs Arch. Pharmacol. 388(2) , 161-73, (2015)

We have developed a method to identify previously undetected histidine and aspartic acid phosphorylations in a human prostate cancer progression model. A phosphoproteome of our cell line model is presented, with correlation of modified protein expression betw...