三羰基环戊二烯合锰

J. Inorg. Biochem. 102(12) , 2114-9, (2008)

Cym-CO-CH2-CH2-COOH was prepared in good yield by Friedel-Crafts reaction of cymantrene (Cym, CpMn(CO)3) with succinic anhydride for the IR labelling of peptides and fully characterized, including an X-ray structure analysis (monoclinic space group P2(1)/n, a...

J. Pharm. Biomed. Anal. 9(10-12) , 965-7, (1991)

Biotin labelled with a cymantrene moiety (cyclopentadienyl manganese tricarbonyl complex) is described for the first time. Because this metallo-biotin retains full recognition for the specific glycoprotein avidin (or streptavidin), the labelled streptavidin-b...

Toxicol. Appl. Pharmacol. 136(2) , 280-8, (1996)

Cyclopentadienyl manganese tricarbonyl (CMT) produces acute pulmonary injury following cytochrome P450 mixed-function oxidase (CYP450) activation. The current studies were designed to characterize the role of hepatic and/or pulmonary CMT activation and the su...

J. Phys. Chem. A 112(41) , 10429-34, (2008)

The standard molar enthalpy of sublimation of monoclinic cyclopentadienyltricarbonylmanganese, Mn(eta (5)-C 5H 5)(CO) 3, at 298.15 K, was determined as Delta sub H m (o)[Mn(eta (5)-C 5H 5)(CO) 3] = 75.97 +/- 0.37 kJ x mol (-1) from Knudsen effusion and Calvet...

Am. Ind. Hyg. Assoc. J. 55(1) , 53-8, (1994)

Occupational and environmental exposure to airborne manganese has been measured for two groups of workers in Montreal, taxi drivers and garage mechanics. In Canada methylcyclopentadienyl manganese tricarbonyl (MMT) has replaced lead as an anti-knock agent in ...

Dalton Trans. 41(21) , 6443-50, (2012)

Organometallic analogues of chloroquine show promise as new antimalarial agents capable of overcoming resistance to the parent drug chloroquine. Here, the synthesis and characterization of three new cymantrene (CpMn(CO)(3)) and cyrhetrene (CpRe(CO)(3)) 4-amin...

J. Immunol. Methods 148(1-2) , 65-75, (1992)

A new non-radioisotopic immunoassay procedure, which we have termed carbonylmetalloimmunoassay (CMIA), is described. The tracers used in this approach are organometallic carbonyl complexes that can be detected at femtomole levels (300-700 fmol) by Fourier tra...

Chemistry 8(11) , 2526-33, (2002)

The syntheses and X-ray crystal structures of [([18]crown-6)2Cs](+)-[Cp3Mn]- (1), [([18]crown-6)2Cs](+)-[Cp'3Mn]- (2), [CsCp'] (3), [(CsCp')2-([18]crown-6)] (4), and Cs[MnCp3] (5), and the synthesis of Cs[MnCp'3] (6) are reported (Cp' = C5H4Me). The anions [C...

Bioconjug. Chem. 21(7) , 1288-96, (2010)

Over the past years, numerous promising new metalorganic lead structures have been developed exhibiting highly active cytostatic properties. However, the efficiency of such chemotherapeutics in the treatment of tumors is often limited by their low therapeutic...

Dalton Trans. 39(10) , 2536-45, (2010)

By combining organometallic groups and peptides, a large number of conjugates with interesting new biological properties can be prepared. Especially, attachment to cell-penetrating peptides (CPP) that act as efficient cell delivery vehicles has come to the fo...