4-羟基吲哚结构式
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常用名 | 4-羟基吲哚 | 英文名 | 4-Hydroxyindole |
|---|---|---|---|---|
| CAS号 | 2380-94-1 | 分子量 | 133.147 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 343.2±15.0 °C at 760 mmHg | |
| 分子式 | C8H7NO | 熔点 | 97-99 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 161.4±20.4 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Characterization of in vitro metabolites of JWH-018, JWH-073 and their 4-methyl derivatives, markers of the abuse of these synthetic cannabinoids
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 957 , 68-76, (2014) • Optimization of a suitable extraction protocol for alkylindoles and their metabolites from biological fluids. • Detection of alkylindoles and their metabolites by means of the GC/MS method adopted by UNODC. • In vitro incubation with human liver microsomes ... |
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Validation and application of an UPLC-MS/MS method for the quantification of synthetic cannabinoids in urine samples and analysis of seized materials from the Portuguese market.
Forensic Sci. Int. 243 , 117-25, (2014) An UPLC-MS/MS method using ESI+ionization and MRM was developed and fully validated according to international guidelines for the qualitative and quantitative analysis of nine synthetic cannabinoids and/or their metabolites in urine samples (1mL). Prior to ex... |
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Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases.
Drug Metab. Dispos. 38(3) , 386-95, (2010) We have examined the glucuronidation of psilocin, a hallucinogenic indole alkaloid, by the 19 recombinant human UDP-glucuronosyltransferases (UGTs) of subfamilies 1A, 2A, and 2B. The glucuronidation of 4-hydroxyindole, a related indole that lacks the N,N-dime... |
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Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A.
J. Med. Chem. 51 , 2634-7, (2008) Synthetic analogues of the sponge natural product exiguamine A (3) have been prepared and evaluated for their ability to inhibit indoleamine 2,3-dioxygenase in vitro. |
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Synthesis and Pharmacological Activity of a New Series of 1-(1H-Indol-4-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol Analogs.
Arch. Pharm. (Weinheim) 349 , 211-23, (2016) β-Adrenergic receptor antagonists are important therapeutics for the treatment of cardiovascular disorders. In the group of β-blockers, much attention is being paid to the third-generation drugs that possess important ancillary properties besides inhibiting β... |
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Determination of selected synthetic cannabinoids and their metabolites by micellar electrokinetic chromatography--mass spectrometry employing perfluoroheptanoic acid-based micellar phase.
Talanta 150 , 568-76, (2016) Perfluoroheptanoic acid was employed as a volatile micellar phase in background electrolyte for micellar electrokinetic chromatography-tandem mass spectrometry separation and determination of 15 selected naphthoyl- and phenylacetylindole- synthetic cannabinoi... |
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Prediction of Setschenow constants of N-heteroaromatics in NaCl solutions based on the partial charge on the heterocyclic nitrogen atom.
Environ. Sci. Pollut. Res. Int. 23 , 3399-405, (2016) The solubilities of 19 different kinds of N-heteroaromatic compounds in aqueous solutions with different concentrations of NaCl were determined at 298.15 K with a UV-vis spectrophotometry and titration method, respectively. Setschenow constants, Ks, were empl... |
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A liquid chromatography-mass spectrometry method based on class characteristic fragmentation pathways to detect the class of indole-derivative synthetic cannabinoids in biological samples.
Anal. Chim. Acta 837 , 70-82, (2014) This article describes a liquid chromatographic/tandem mass spectrometric method, based on the use of precursor ion scan as the acquisition mode, specifically developed to detect indole-derived cannabinoids (phenylacetylindoles, naphthoylindoles and benzoylin... |