三氟乙醇

一般危化品
三氟乙醇结构式
三氟乙醇结构式
常用名 三氟乙醇 英文名 2,2,2-Trifluoroethanol
CAS号 75-89-8 分子量 100.040
密度 1.393 沸点 77-80 ºC
分子式 C2H3F3O 熔点 -45 ºC
MSDS 中文版 美版 闪点 29 ºC
符号 GHS02 GHS05 GHS06
GHS02, GHS05, GHS06
信号词 Danger

Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections.

Pharm. Res. 32(5) , 1546-56, (2015)

To investigate the suitability of three antimicrobial peptides (AMPs) as cell-penetrating antimicrobial peptides.Cellular uptake of three AMPs (PK-12-KKP, SA-3 and TPk) and a cell-penetrating peptide (penetratin), all 5(6)-carboxytetramethylrhodamine-labeled,...

Quantification of serum IgG subclasses by use of subclass-specific tryptic peptides and liquid chromatography--tandem mass spectrometry.

Clin. Chem. 60(8) , 1080-8, (2014)

Measurement of IgG subclasses is a useful tool for investigation of humoral immune deficiency in the presence of total IgG within reference intervals and IgG4-related disease. Nephelometry has been the method of choice for quantification. We describe an LC-MS...

Metrological traceability in mass spectrometry-based targeted protein quantitation: a proof-of-principle study for serum apolipoproteins A-I and B100.

J. Proteomics 109 , 143-61, (2014)

In this study, we have followed up on previous liquid chromatography (LC) multiple reaction monitoring (MRM) mass spectrometry (MS) approaches for measurement of apolipoprotein (apo) A-I and apo B100 in serum aiming for implementation of a multiplexed assay i...

Water plays an important role in osmolyte-induced hairpin structure change: a molecular dynamics simulation study.

J. Chem. Phys. 137(14) , 145101, (2012)

To investigate how solvent (water) and cosolvent (osmolyte) affect protein structure in various osmolyte solutions, in the present study we used GB1p peptide as the model protein to study its folding process in 2,2,2-trifluoroethanol (TFE)∕water and denaturat...

Visualizing the Inner Architecture of Poly(ϵ-caprolactone)-Based Biomaterials and Its Impact on Performance Optimization.

Macromol. Biosci. 15 , 1554-62, (2015)

The performance of poly(ϵ-caprolactone) (PCL)-based biomaterials is defined by spatial distributions of PCL's amorphous and crystalline domains. Unfortunately, directly visualizing their inner architectures has been challenging. This study demonstrates, the s...

Substantial Differentiation of Human Neural Stem Cells Into Motor Neurons on a Biomimetic Polyurea.

Macromol. Biosci. 15 , 1206-11, (2015)

To find the first restorative treatment for spinal cord injury (SCI), researchers have focused on stem cell therapies. However, one obstacle is the lack of an implantable cell scaffold that can support efficient motor neuron (MN) differentiation and prolifera...

Unraveling the interplay of backbone rigidity and electron rich side-chains on electron transfer in peptides: the realization of tunable molecular wires.

J. Am. Chem. Soc. 136(35) , 12479-88, (2014)

Electrochemical studies are reported on a series of peptides constrained into either a 310-helix (1-6) or β-strand (7-9) conformation, with variable numbers of electron rich alkene containing side chains. Peptides (1 and 2) and (7 and 8) are further constrain...

Measuring the relative hydrogen-bonding strengths of alcohols in aprotic organic solvents.

ChemPhysChem 16(1) , 160-8, (2015)

Voltammetric experiments with 9,10-anthraquinone and 1,4-benzoquinone performed under controlled moisture conditions indicate that the hydrogen-bond strengths of alcohols in aprotic organic solvents can be differentiated by the electrochemical parameter ΔEp (...

Mimicking and Understanding the Agglutination Effect of the Antimicrobial Peptide Thanatin Using Model Phospholipid Vesicles.

Biochemistry 54 , 3932-41, (2015)

Thanatin is a cationic 21-residue antimicrobial and antifongical peptide found in the spined soldier bug Podisus maculiventris. It is believed that it does not permeabilize membranes but rather induces the agglutination of bacteria and inhibits cellular respi...

The structure and mechanical properties of the proteins of lamprey cartilage.

Biopolymers 103(4) , 187-202, (2015)

The cyanogen bromide-resistant proteins of lamprey cartilage are biochemically related to the mammalian elastic protein, elastin. This study investigates their mechanical properties and enquires whether, like elastin, long-range elasticity arises in them from...