醋酸环丙孕酮

醋酸环丙孕酮结构式
醋酸环丙孕酮结构式
品牌特惠专场
常用名 醋酸环丙孕酮 英文名 Cyproterone acetate
CAS号 427-51-0 分子量 402.91
密度 1.3±0.1 g/cm3 沸点 525.9±50.0 °C at 760 mmHg
分子式 C23H27ClO4 熔点 200-201ºC
MSDS 中文版 美版 闪点 177.6±29.1 °C
符号 GHS07 GHS08
GHS07, GHS08
信号词 Warning

Estrogen and androgen regulate actin-remodeling and endocytosis-related genes during rat spermiation.

Mol. Cell. Endocrinol. 404 , 91-101, (2015)

Spermiation, the sperm release process, is imperative to male fertility and reproduction. Morphologically, it is characterized by removal of atypical adherens junctions called ectoplasmic specializations, and formation of transient endocytic devices called tu...

Effects of the anti-androgen cyproterone acetate (CPA) on oocyte meiotic maturation in rainbow trout (Oncorhynchus mykiss).

Aquat. Toxicol. 164 , 34-42, (2015)

In the present study, we aimed at characterizing the effect of cyproterone acetate (CPA), an anti-androgenic compound, on oocyte meiotic maturation in a freshwater teleost fish species, the rainbow trout (Oncorhynchus mykiss). Fully-grown post-vitellogenic ov...

Preservation of volumetric bone density and geometry in trans women during cross-sex hormonal therapy: a prospective observational study.

Osteoporos. Int. 26(1) , 35-47, (2015)

Although trans women before the start of hormonal therapy have a less bone and muscle mass compared with control men, their bone mass and geometry are preserved during the first 2 years of hormonal therapy, despite of substantial muscle loss, illustrating the...

High-content positional biosensor screening assay for compounds to prevent or disrupt androgen receptor and transcriptional intermediary factor 2 protein-protein interactions.

Assay Drug Dev. Technol. 12(7) , 395-418, (2014)

The androgen receptor-transcriptional intermediary factor 2 (AR-TIF2) positional protein-protein interaction (PPI) biosensor assay described herein combines physiologically relevant cell-based assays with the specificity of binding assays by incorporating str...

The Relationship Between Dermatologist- and Patient-Reported Acne Severity Measures and Treatment Recommendations.

J. Cutan. Med. Surg. 19 , 464-9, (2015)

Acne treatment recommendations for individual patients may be derived from multiple factors including dermatologist- and patient-reported constructs.To evaluate the effects of dermatologist- and patient-reported measures on acne treatment recommendations by d...

Bioefficacy of hydromethanolic extract of tuber of Chlorophytum borivilianum (Safed Musli) for the management of male infertility in cyproterone acetate-treated albino rats.

Andrologia 46(6) , 659-71, (2014)

Increase in male sexual dysfunction, and its treatment with conventional aphrodisiac drugs with side effects lead to investigate the spermatogenesis and androgenesis augmentative efficacy of hydromethanolic (40 : 60) extract of root of Chlorophytum borivilian...

Cross-platform toxicogenomics for the prediction of non-genotoxic hepatocarcinogenesis in rat.

PLoS ONE 9(5) , e97640, (2014)

In the area of omics profiling in toxicology, i.e. toxicogenomics, characteristic molecular profiles have previously been incorporated into prediction models for early assessment of a carcinogenic potential and mechanism-based classification of compounds. Tra...

Menopause management: how you can do better.

J. Fam. Pract. 61(3) , 138-45, (2012)

Let patients know that hot flashes, vaginal dryness, and other common menopausal symptoms can be treated successfully with hormonal and nonhormonal agents.

Testosterone treatment is a potent tumor promoter for the rat prostate.

Endocrinology 155(12) , 4629-33, (2014)

Testosterone is increasingly prescribed to middle aged and older men, but the safety of this treatment has been called into question, and the possible risk of prostate cancer is unknown. We treated Wistar Cpb: WU rats chronically via slow-release Silastic imp...

Stimulation of cannabinoid receptors by using Rubus coreanus extracts to control osteoporosis in aged male rats.

Aging Male 18 , 124-32, (2015)

A substantial proportion of men with prostatic disease have an increased risk of bone loss. In the present study, we investigated the effects of Rubus coreanus Miquel (RCM) extracts on osteoporosis that occurs with N-methyl-N-nitrosourea (MNU)-induced prostat...