布洛芬钠盐
布洛芬钠盐结构式
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常用名 | 布洛芬钠盐 | 英文名 | ibuprofen sodium salt |
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| CAS号 | 31121-93-4 | 分子量 | 228.26300 | |
| 密度 | 1.029g/cm3 | 沸点 | 319.6ºC at 760 mmHg | |
| 分子式 | C13H17NaO2 | 熔点 | 75-77ºC | |
| MSDS | 美版 | 闪点 | 216.7ºC |
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The advantages and limitations of the analgesics available for control of postoperative pain after a dental procedure.
SAAD Dig. 29 , 70-81, (2013)
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Enhanced longevity by ibuprofen, conserved in multiple species, occurs in yeast through inhibition of tryptophan import.
PLoS Genet. 10(12) , e1004860, (2014) The common non-steroidal anti-inflammatory drug ibuprofen has been associated with a reduced risk of some age-related pathologies. However, a general pro-longevity role for ibuprofen and its mechanistic basis remains unclear. Here we show that ibuprofen incre... |
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Pegylation improves the pharmacokinetics and bioavailability of small-molecule drugs hydrolyzable by esterases: a study of phospho-Ibuprofen.
J. Pharmacol. Exp. Ther. 351(1) , 61-6, (2014) Esterase hydrolysis of drugs can accelerate their elimination, thereby limiting their efficacy. Polyethylene glycol (PEG) covalently attached to drugs (pegylation) is known to improve the efficiency of many drugs. Using as a test agent the novel phospho-ibupr... |
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Development and pharmacological characterization of a model of sleep disruption-induced hypersensitivity in the rat.
Eur. J. Pain 19(4) , 554-66, (2015) Sleep disturbance is a commonly reported co-morbidity in chronic pain patients, and conversely, disruption of sleep can cause acute and long-lasting hypersensitivity to painful stimuli. The underlying mechanisms of sleep disruption-induced pain hypersensitivi... |
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An investigation into the drug release from ibuprofen matrix tablets with ethylcellulose and some poly-acrylate polymers.
Pak. J. Pharm. Sci. 27(3) , 495-503, (2014) This study was performed to achieve sustained-release Ibuprofen matrix tablets with a zero-order release kinetic while most of the previous formulations have shown Higuchi release kinetic. Considering the results from previous studies, ethyl cellulose, Carbop... |
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Influence of beta-cyclodextrin and chitosan in the formulation of a colon-specific drug delivery system.
Drug Res. (Stuttg.) 63(12) , 657-62, (2013) The increase in diseases of the colon underscores the need to develop cost-effective site-directed therapies. We formulated a polysaccharide-based matrix system that could release ibuprofen under conditions simulating those in the colon by employing a wet gra... |
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Effects of ibuprofen, diclofenac, naproxen, and piroxicam on the course of pregnancy and pregnancy outcome: a prospective cohort study.
BJOG 120(8) , 948-59, (2013) To investigate the individual effects of ibuprofen, diclofenac, naproxen, and piroxicam on pregnancy outcome.Cohort study.Norwegian population.A total of 90 417 women and singleton child pairs.The Norwegian Mother and Child Cohort Study and Medical Birth Regi... |
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Gelatine enhances drug dispersion in alginate bilayer film via the formation of crystalline microaggregates.
Int. J. Pharm. 454(1) , 99-106, (2013) In our previous study, a novel alginate-based bilayer film for slow-release wound dressings was successfully developed. We found that alginate alone yielded poor films; however, the addition of gelatine had significantly enhanced the drug dispersion as well a... |
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Pharmaceuticals in the freshwater invertebrate, Gammarus pulex, determined using pulverised liquid extraction, solid phase extraction and liquid chromatography-tandem mass spectrometry.
Sci. Total Environ. 511 , 153-60, (2015) The development, characterisation and application of a new analytical method for multi-residue PPCP determination in the freshwater amphipod, Gammarus pulex are presented. Analysis was performed using pulverised liquid extraction (PuLE), solid phase extractio... |
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Occurrence and distribution of pharmaceutically active and endocrine disrupting compounds in Singapore's marine environment: influence of hydrodynamics and physical-chemical properties.
Environ. Pollut. 182 , 1-8, (2013) The fate and exposure risks of pharmaceutically active compounds (PhACs) and endocrine disrupting chemicals (EDCs) in marine environments are not well-understood. In this study we developed a multi-residue analytical method for quantifying concentrations of f... |