异硫氰酸荧光素酯
异硫氰酸荧光素酯结构式
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常用名 | 异硫氰酸荧光素酯 | 英文名 | Fluorescein isothiocyanate |
|---|---|---|---|---|
| CAS号 | 3326-32-7 | 分子量 | 389.381 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 708.6±60.0 °C at 760 mmHg | |
| 分子式 | C21H11NO5S | 熔点 | >360 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 382.4±32.9 °C | |
| 符号 |
GHS08 |
信号词 | Danger |
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Imaging of a clinically relevant stroke model: glucose hypermetabolism revisited.
Stroke 46(3) , 835-42, (2015) Ischemic stroke has been shown to cause hypermetabolism of glucose in the ischemic penumbra. Experimental and clinical data indicate that infarct-related systemic hyperglycemia is a potential therapeutic target in acute stroke. However, clinical studies aimin... |
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Surface modifications of silica nanoparticles are crucial for their inert versus proinflammatory and immunomodulatory properties.
Int. J. Nanomedicine 9 , 2815-32, (2014) Silica (SiO₂) nanoparticles (NPs) are widely used in diverse industrial and biomedical applications. Their applicability depends on surface modifications, which can limit potential health problems.To assess the potential impact of SiO₂ NP exposure and NPs che... |
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Uptake of neutrophil-derived Ym1 protein distinguishes wound macrophages in the absence of interleukin-4 signaling in murine wound healing.
Am. J. Pathol. 184(12) , 3249-61, (2014) The determination of regenerative wound-healing macrophages as alternatively activated macrophages is currently questioned by the absence of IL-4 in wound tissue. Yet, murine wound tissue expressed high levels of Ym1 (chitinase 3-like 3), an established marke... |
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Brain pericyte-derived soluble factors enhance insulin sensitivity in GT1-7 hypothalamic neurons.
Biochem. Biophys. Res. Commun. 457(4) , 532-7, (2015) Insulin signaling in the hypothalamus plays an important role in food intake and glucose homeostasis. Hypothalamic neuronal functions are modulated by glial cells; these form an extensive network connecting the neurons and cerebral vasculature, known as the n... |
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Evaluation of a dental pulp-derived cell sheet cultured on amniotic membrane substrate.
Biomed Mater Eng 25(2) , 203-12, (2015) Mesenchymal stem cells (MSC) are transplanted for periodontal tissue regeneration, and the periodontal ligament (PDL) is regenerated using a cultured cell sheet. This cultured cell sheet is prepared using PDL-derived cells, growth factors, and amniotic membra... |
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Hepatitis C virus entry is impaired by claudin-1 downregulation in diacylglycerol acyltransferase-1-deficient cells.
J. Virol. 88(16) , 9233-44, (2014) Diacylglycerol acyltransferase-1 (DGAT1) is involved in the assembly of hepatitis C virus (HCV) by facilitating the trafficking of the HCV core protein to the lipid droplet. Here, we abrogated DGAT1 expression in Huh-7.5 cells by using either the transcriptio... |
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Oral delivery of probiotic expressing M cell homing peptide conjugated BmpB vaccine encapsulated into alginate/chitosan/alginate microcapsules.
Eur. J. Pharm. Biopharm. 88(3) , 768-77, (2014) Oral administration of live probiotics as antigen delivery vectors is a promising approach in vaccine development. However, the low survival of probiotics in the gastrointestinal tract limits this approach. Therefore, the aim of this study was the encapsulati... |
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Dual growth factor-immobilized microspheres for tissue reinnervation: in vitro and preliminary in vivo studies.
J. Biomater. Sci. Polym. Ed. 26(5) , 322-37, (2015) Growth factors (GFs) (basic fibroblast growth factor (bFGF) and/or nerve growth factor (NGF))-immobilized polycaprolactone (PCL)/Pluronic F127 microspheres were prepared using an isolated particulate-melting method and the sequential binding of heparin and GF... |
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Omega-3 fatty acids, EPA and DHA induce apoptosis and enhance drug sensitivity in multiple myeloma cells but not in normal peripheral mononuclear cells.
J. Nutr. Biochem. 25(12) , 1254-62, (2014) The n-3 polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been shown to enhance the effect of chemotherapeutic drugs in clinical studies in cancer patients and to induce apoptotic tumor cell death in vitro. Until now,... |
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Glucose intolerance in aging male IGFBP-3 transgenic mice: differential effects of human IGFBP-3 and its mutant IGFBP-3 devoid of IGF binding ability.
Endocrinology 156(2) , 462-74, (2015) We have reported a reduction of insulin secretion and glucose intolerance in young mice overexpressing human IGFBP-3 (phosphoglycerate kinase [PGK]BP3) or its mutant Gly56/Gly80/Gly81-IGFBP-3 (PGKmutBP3) under the PGK promoter. Here, we investigated changes i... |