苯赖加压素

J. Pharm. Sci. 103(7) , 2053-61, (2014)

The pH partition theory proposes a correlation between fraction of unionized drug substance and permeability. The aim of this study was to compare the permeability of metoprolol and mannitol in ex vivo human and porcine buccal mucosa models at varying pH to v...

Cochrane Database Syst. Rev. 12 , CD009742, (2014)

Whilst carrying out dental procedures under general anaesthesia (GA), practitioners routinely give local anaesthetics (LA) intraoperatively to children. Local anaesthetics are used to help manage postoperative pain and reduce bleeding and the physiological re...

Regul. Pept. 115(2) , 139-49, (2003)

A novel member of the vasopressin/oxytocin superfamily, octopressin (OP), has been isolated from Octopus vulgaris. Since another peptide of this superfamily, cephalotocin (CT), was isolated from the same species [Neurosci. Lett. 134 (1992) 191], Octopus has t...

Br. Dent. J. 192(3) , 161-3, (2002)

To investigate the cardiovascular responses of cardiac transplant recipients to dental local anaesthetic solutions with and without epinephrine (adrenaline).A clinical study employing 30 patients (20 cardiac transplant recipients and ten healthy) awaiting gin...

Int. Endod. J. 34(6) , 440-6, (2001)

The purpose of this study was to evaluate clinically and radiographically pulpotomies carried out under intrapulpal injection of anaesthetic solution.Forty-one permanent mandibular molar teeth presenting with deep carious lesions and/or exposed pulps, with or...

Int. Immunopharmacol. 1(5) , 911-23, (2001)

In vitro treatment of macrophages with lidocaine-epinephrine or prilocaine-felypressine resulted in inhibition of their adhesion, chemotaxis and phagocytosis. However, prilocaine-felypressine was a much more potent inhibitor of adhesion and phagocytosis than ...

Pharmacol. Res. 46(1) , 15-8, (2002)

Some reports have demonstrated that the vasoconstrictor effect of catecholamines may be amplified by felypressin. Thus, the association of felypressin and epinephrine with local anesthetics may be indicated to achieve more effective vasoconstrictor actions wi...

Pharmacol. Res. 46(2) , 107-11, (2002)

Vasoconstrictor substances, as norepinephrine and epinephrine, were mixtured to local anesthetics to decrease their toxic effects and to prolong the depth of the anesthesia. However, these catecholamines produce systolic and diastolic hypertension. The effect...

Pharmacol. Res. 48(4) , 325-8, (2003)

This study aimed to observe the effects of prilocaine chloridate (P) and the associations of P with felypressin (P+F), and epinephrine (P+E) on the heart rate and force of contraction on the isolated hearts of rats. The hearts were perfused according to Lange...

Eur. J. Oral Sci. 111(4) , 339-45, (2003)

The authors investigated the effects of felypressin (Fely), a non-adrenergic vasoconstrictor, used together with prilocaine on myocardial oxygen balance. Six open-chest dogs were studied under urethane and alpha-chloralose anesthesia. Systolic arterial pressu...