1-(4,4'-二氟苯甲基)哌嗪结构式
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常用名 | 1-(4,4'-二氟苯甲基)哌嗪 | 英文名 | 1-(bis(4-fluorophenyl)methyl)piperazine |
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CAS号 | 27469-60-9 | 分子量 | 288.335 | |
密度 | 1.2±0.1 g/cm3 | 沸点 | 367.9±37.0 °C at 760 mmHg | |
分子式 | C17H18F2N2 | 熔点 | 88-92 °C(lit.) | |
MSDS | N/A | 闪点 | 176.3±26.5 °C | |
符号 |
GHS06 |
信号词 | Danger |
Oxidative metabolism of flunarizine in rat liver microsomes.
Res. Commun. Chem. Pathol. Pharmacol. 78(1) , 85-95, (1992) The oxidative metabolism of flunarizine [1-[bis(4-fluorophenyl)-methyl]-4-(3-phenyl-2-propenyl)piperazine, FZ] to 1-[bis-(4-fluorophenyl)methyl]piperazine (M-1), 1-[bis(4-fluorophenyl)methyl]-4-[3-(4'-hydroxyphenyl)-2- propenyl]piperazine (M-2) and 4,4'-diflu... |
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Lipidosis of the dorsal root ganglia in rats treated with an almitrine metabolite.
Arch. Toxicol. 69(6) , 391-6, (1995) Toxic effects of a detriazinyl metabolite of almitrine (DTMA) were evaluated in rats and on cultured rat macrophages. In rats daily treated with DTMA for 16 weeks, spastic gaits with heel-lifting appeared, and lamellated and/or crystalloid bodies formed in se... |