1-(4,4'-二氟苯甲基)哌嗪

1-(4,4'-二氟苯甲基)哌嗪结构式
1-(4,4'-二氟苯甲基)哌嗪结构式
品牌特惠专场
常用名 1-(4,4'-二氟苯甲基)哌嗪 英文名 1-(bis(4-fluorophenyl)methyl)piperazine
CAS号 27469-60-9 分子量 288.335
密度 1.2±0.1 g/cm3 沸点 367.9±37.0 °C at 760 mmHg
分子式 C17H18F2N2 熔点 88-92 °C(lit.)
MSDS N/A 闪点 176.3±26.5 °C
符号 GHS06
GHS06
信号词 Danger

Oxidative metabolism of flunarizine in rat liver microsomes.

Res. Commun. Chem. Pathol. Pharmacol. 78(1) , 85-95, (1992)

The oxidative metabolism of flunarizine [1-[bis(4-fluorophenyl)-methyl]-4-(3-phenyl-2-propenyl)piperazine, FZ] to 1-[bis-(4-fluorophenyl)methyl]piperazine (M-1), 1-[bis(4-fluorophenyl)methyl]-4-[3-(4'-hydroxyphenyl)-2- propenyl]piperazine (M-2) and 4,4'-diflu...

Lipidosis of the dorsal root ganglia in rats treated with an almitrine metabolite.

Arch. Toxicol. 69(6) , 391-6, (1995)

Toxic effects of a detriazinyl metabolite of almitrine (DTMA) were evaluated in rats and on cultured rat macrophages. In rats daily treated with DTMA for 16 weeks, spastic gaits with heel-lifting appeared, and lamellated and/or crystalloid bodies formed in se...