2-氨基-2-甲基-1-丙醇

Bioconjug. Chem. 26(2) , 286-93, (2015)

Bone morphogenetic protein-2 (BMP-2) plays an important role in bone and cartilage formation and is of interest in regenerative medicine. Heparin can interact electrostatically with BMP-2 and thus has been explored for controlled release and potential stabili...

Bone 79 , 43-51, (2015)

Osteoporosis is the consequence of altered bone metabolism resulting in the systemic reduction of bone strength and increased risk of fragility fractures. MicroRNAs (miRNAs) regulate gene expression on a post-transcriptional level and are known to take part i...

Toxicol. Mech. Methods 18 , 217-27, (2008)

ABSTRACT Drug-induced phospholipidosis (PL) is a condition characterized by the accumulation of phospholipids and drug in lysosomes, and is found in a variety of tissue types. PL is frequently manifested in preclinical studies and may delay or prevent the dev...

Clin. Chim. Acta 411(11-12) , 882-5, (2010)

Background Harmonization of results allows a more effective utilization of laboratory tests; we verified the feasibility of harmonizing serum alkaline phosphatase results by two methods.

J. Environ. Sci. (China) 24(5) , 897-902, (2012)

Aqueous 1,8-diamino-p-menthane (KIER-C3) and commercially available amine solutions were tested for CO2 absorption. A 2-amino-2-methyl-1-propanol (AMP) solution with an addition of KIER-C3 showed 9.3% and 31.6% higher absorption rate for CO2 than the AMP solu...

Clin. Chem. 38(11) , 2286-94, (1992)

We evaluated N-methyl-D-glucamine (MEG) as a buffer for assay of alkaline phosphatase (ALP; EC 3.1.3.1) and compared the MEG-based assay with the current International Federation of Clinical Chemistry Reference Method for ALP (IFCC/RM/ALP), in which 2-amino-2...

Ann. Clin. Biochem. 35 ( Pt 1) , 120-7, (1998)

Most UK clinical laboratories use alkaline phosphatase (ALP) methods similar to that proposed by the International Federation of Clinical Chemistry (IFCC), based on the use of 2-amino-2-methyl-1-propanol (AMP) buffer. We present evidence of significant differ...

J. Biotechnol. 114(1-2) , 209-17, (2004)

The synthesis of levan using a levansucrase from a strain of Bacillus subtilis was studied in the presence of the water-miscible solvents: acetone, acetonitrile and 2-methyl-2-propanol (2M2P). It was found that while the enzyme activity is only slightly affec...

Chemosphere 77(10) , 1352-7, (2009)

Absolute rate constants for the reaction of three important degradation products of methyl-tert-butyl ether (MTBE) with the hydroxyl radical, hydrated electron and hydrogen atom were determined in aqueous solution at room temperature. These three intermediate...

Food Chem. Toxicol. 46(2) , 678-87, (2008)

This study determined the oral and dermal ADME of 2-amino-2-methyl-1-propanol (AMP), a substituted aliphatic alcohol used in a number of industrial and consumer products. Groups of 4 male Fischer 344 rats received either a single bolus oral or dermal dose of ...