氧氯丙嗪

Se Pu 30(9) , 938-42, (2012)

Based on the phenomenon that each of chlorpromazine (CPZ), promethazine (PMZ), chlorpromazine sulfoxide (CPZSO) and promethazine sulfoxide (PMZSO) could enhance the electrochemiluminescence (ECL) intensity of tris(2,2'-bipyridyl) ruthenium, a novel and sensit...

Photochem. Photobiol. 44(1) , 5-10, (1986)

Biochemistry 26(25) , 8133-7, (1987)

The effects of phenothiazines (chlorpromazine, chlorpromazine sulfoxide, and trifluoperazine) and antimitotic drugs (colchicine and vinblastine) on the erythrocyte membrane have been investigated. Chlorpromazine and trifluoperazine induced a dose-dependent in...

Ther. Drug Monit. 9(3) , 358-65, (1987)

A new high-performance liquid chromatographic (HPLC) procedure for the simultaneous determination of chlorpromazine and its six metabolites, namely, 7-hydroxy-chlorpromazine, N-monodesmethyl-chlorpromazine, 7-hydroxy-N-monodesmethyl-chlorpromazine, chlorproma...

Ther. Drug Monit. 7(4) , 472-7, (1985)

Pooled whole blood from healthy volunteers was spiked with pure, synthetic chlorpromazine, chlorpromazine sulfoxide, or chlorpromazine N-oxide and then made alkaline with either sodium hydroxide or sodium carbonate. The addition of alkali causes lysis of red ...

Int. J. Legal Med. 123(3) , 247-52, (2009)

On-site drug screening devices are widely used today for their simple test procedures and instantaneous results. Among other devices, a Triage Drug of Abuse panel is considered to be highly reliable for its high specificity and sensitivity of abused drugs. Al...

Ther. Drug Monit. 8(1) , 37-41, (1986)

Chlorpromazine (CPZ), chlorpromazine sulfoxide (CPZSO), and chlorpromazine N-oxide (CPZNO) were each incubated (37 degrees C), for various timed intervals up to 60 min, with pooled human whole blood. Plasma and red blood cells were then separated and analyzed...

Naunyn Schmiedebergs Arch. Pharmacol. 333(4) , 454-6, (1986)

Treatment of frog cutaneous-pectoris nerve-muscle preparations with calmidazolium (R 24571), a calmodulin-inhibitor, at concentrations of 2 X 10(-7) mol/l and 5 X 10(-7) mol/l had no discernable effect on MEPP amplitude. 10(-6) mol/l calmidazolium caused a sm...

Brain Res. 273(2) , 384-6, (1983)

Trifluoperazine and chlorpromazine, blockers of calmodulin action, potentiate slow inward current in molluscan neurons identically to the action of cAMP. The sulfoxide derivative of chloropromazine does not appreciably bind to calmodulin and also fails to enh...

Brain Res. 437(2) , 397-401, (1987)

Treatment of frog neuromuscular preparations with chlorpromazine (5 mumol/l) resulted in a marked rise in miniature endplate potential (MEPP) frequency of greater than 100% within 30 min, and an increase in evoked transmitter release (quantal content 5-15) of...