甲羟苯丙胺
甲羟苯丙胺结构式
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常用名 | 甲羟苯丙胺 | 英文名 | Pholedrine |
|---|---|---|---|---|
| CAS号 | 370-14-9 | 分子量 | 165.23200 | |
| 密度 | 1.014g/cm3 | 沸点 | 279.4ºC at 760mmHg | |
| 分子式 | C10H15NO | 熔点 | 162-163° | |
| MSDS | 中文版 美版 | 闪点 | 109ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Identification of new urinary metabolites of famprofazone in humans.
J. Anal. Toxicol. 22(1) , 55-60, (1998) Urinary metabolites of famprofazone following oral administration in humans were identified by gas chromatography-mass spectrometry with electron impact-ionization and comparison with the spectra and retention times of authentic standards. The metabolites wer... |
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Urinary excretion of the main metabolites of methamphetamine, including p-hydroxymethamphetamine-sulfate and p-hydroxymethamphetamine-glucuronide, in humans and rats.
Xenobiotica 36(2-3) , 259-67, (2006) The urinary concentrations of the main metabolites of methamphetamine (MA), specifically p-hydroxymethamphetamine-sulfate (p-OHMA-Sul) and p-hydroxymethamphetamine-glucuronide (p-OHMA-Glu), were directly measured in MA users and rats using an optimized LC-ESI... |
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LC-MS/MS analysis of pholedrine in a fatal intoxication case.
Forensic Sci. Int. 133(1-2) , 101-6, (2003) Pholedrine (4'-hydroxymethamphetamine) is a cardiovascular agent exerting hypertensive and adrenergic effects. High doses may cause a drop in the peripheral circulation blood flow and increase blood pressure, heart rate and body temperature up to a state of c... |
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Interaction of 3,4-methylenedioxymethamphetamine and methamphetamine during metabolism by in vitro human metabolic enzymes and in rats.
J. Forensic Sci. 57(4) , 1008-13, (2012) Illicit amphetamine-type stimulant (ATS) tablets commonly contain one or more active ingredients, which have hallucinogenic and/or stimulant effects. Because components such as 3,4-methylenedioxymethamphetamine (MDMA) and methamphetamine (MA) in ATS tablets h... |
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p-Hydroxymethamphetamine enantiomer pharmacokinetics and metabolism in rats: absence of N-demethylation.
Biopharm. Drug Dispos. 18(5) , 423-32, (1997) p-hydroxymethamphetamine (OHMAP) is one of the major metabolites of the widely abused drug methamphetamine (MAP). The demethylation of OHMAP to p-hydroxyamphetamine (OHAP) has been shown in vitro but has never been reported in vivo. The disposition kinetics a... |
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[Horner's syndrome secondary to ophthalmic herpes zoster].
Rev. Neurol. 25(148) , 1922-4, (1997) Ophthalmoparesias is a frequent complication of ophthalmic herpes zoster. It occurs in 31% of all cases. However, the presence of Horner's syndrome during viral reactivation is a rarity which has only been previously described on two occasions, and never asso... |
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Direct determination of p-hydroxymethamphetamine glucuronide in human urine by high-performance liquid chromatography.
Chem. Pharm. Bull. 54(4) , 493-5, (2006) High-performance liquid chromatography (HPLC) with UV detection for the simultaneous determination of the free form of p-hydroxymethamphetamine (p-OHMA) and its metabolite, glucuronide (p-OHMAG) was accomplished for the first time. We achieved this by employi... |
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HIV-negative drug addict diagnosed with AIDS and tuberculosis at autopsy: a case report and brief review of literature.
J. Forensic Leg. Med. 18(3) , 136-8, (2011) Human Immunodeficiency Virus (HIV) infection is a true plague and a major health concern globally. It is one of the most significant pandemics in recorded history. Despite worldwide efforts to fight the pandemic, and now with the re-emergence of tuberculosis,... |
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Fluorescence analysis of p-hydroxymethamphetamine in urine by thin-layer chromatography.
Anal. Sci. 21(9) , 1117-9, (2005) A highly-sensitive analytical method for the detection of p-hydroxymethamphetamine (pOHMA) in urine is presented. The proposed method combines liquid-liquid extraction with acetonitrile and solid-phase extraction by thin-layer chromatography (TLC) with oxidat... |
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Radioimmunoassay for the determination of pholedrine.
Pharmazie 52(12) , 937-9, (1997) A radioimmunoassay for the determination of free pholedrine at the lower nanogram level was developed. The sulfate conjugate cross-reacts and has to be separated before the assay procedure in plasma. |