维生素b12
维生素b12结构式
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常用名 | 维生素b12 | 英文名 | Vitamin B12 |
|---|---|---|---|---|
| CAS号 | 68-19-9 | 分子量 | 1355.365 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C63H88CoN14O14P | 熔点 | >300ºC | |
| MSDS | 中文版 美版 | 闪点 | 9 °C | |
| 符号 |
GHS02, GHS06, GHS08 |
信号词 | Danger |
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Alanine Scanning Mutagenesis Identifies an Asparagine–Arginine–Lysine Triad Essential to Assembly of the Shell of the Pdu Microcompartment
J. Mol. Biol. 426(12) , 2328-45, (2014) Bacterial microcompartments (MCPs) are the simplest organelles known. They function to enhance metabolic pathways by confining several related enzymes inside an all-protein envelope called the shell. In this study, we investigated the factors that govern MCP ... |
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Tissue vitamin concentrations are maintained constant by changing the urinary excretion rate of vitamins in rats' restricted food intake.
Biosci. Biotechnol. Biochem. 78(12) , 2102-9, (2014) We previously reported that mild food restriction induces a reduction in tryptophan-nicotinamide conversion, which helps to explain why death secondary to pellagra is pandemic during the hungry season. In this study, we investigated the levels of B-group vita... |
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Effect of concentrate feeder design on performance, eating and animal behavior, welfare, ruminal health, and carcass quality in Holstein bulls fed high-concentrate diets.
J. Anim. Sci. 93 , 3018-33, (2015) A total of 240 Holstein bulls (121 ± 2.0 kg initial BW; 99 ± 1.0 d of age), from 2 consecutive fattening cycles, were randomly allocated in 1 of 6 pens and assigned to 1 of the 3 treatments consisting of different concentrate feeder designs: a control feeder ... |
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Solubilization of gliadins for use as a source of nitrogen in the selection of bacteria with gliadinase activity.
Food Chem. 168 , 439-44, (2014) For patients with celiac disease, gliadin detoxification via the use of gliadinases may provide an alternative to a gluten-free diet. A culture medium, in which gliadins were the sole source of nitrogen, was developed for screening for microorganisms with gli... |
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Disease mutations in desmoplakin inhibit Cx43 membrane targeting mediated by desmoplakin-EB1 interactions.
J. Cell Biol. 206(6) , 779-97, (2014) Mechanisms by which microtubule plus ends interact with regions of cell-cell contact during tissue development and morphogenesis are not fully understood. We characterize a previously unreported interaction between the microtubule binding protein end-binding ... |
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Biomarkers of one-carbon metabolism are associated with biomarkers of inflammation in women.
J. Nutr. 144(5) , 714-21, (2014) Folate-mediated one-carbon metabolism is essential for DNA synthesis, repair, and methylation. Perturbations in one-carbon metabolism have been implicated in increased risk of some cancers and may also affect inflammatory processes. We investigated these inte... |
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Circulating biomarkers of one-carbon metabolism in relation to renal cell carcinoma incidence and survival.
J. Natl. Cancer Inst. 106(12) , doi:10.1093/jnci/dju327, (2014) The etiology of renal cell carcinoma (RCC) is only partially understood, but a metabolic component appears likely. We investigated biomarkers of one-carbon metabolism and RCC onset and survival.The European Prospective Investigation into Cancer and Nutrition ... |
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In vivo doses of butadiene epoxides as estimated from in vitro enzyme kinetics by using cob(I)alamin and measured hemoglobin adducts: an inter-species extrapolation approach.
Toxicol. Appl. Pharmacol. 281(3) , 276-84, (2014) 1,3-Butadiene (BD) is a rodent and human carcinogen. In the cancer tests, mice have been much more susceptible than rats with regard to BD-induced carcinogenicity. The species-differences are dependent on metabolic formation/disappearance of the genotoxic BD ... |
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VB12-coated Gel-Core-SLN containing insulin: Another way to improve oral absorption.
Int. J. Pharm. 493 , 451-9, (2015) To improve the oral absorption of insulin, a novel carrier of Vitamin B12 (VB12) gel core solid lipid nanopaticles (Gel-Core-SLN, GCSLN) was designed with a gel core, lipid matrix and VB12-coated surface. VB12-stearate was synthesized and characterized by inf... |
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Hyperhomocysteinemia and assessment of its associated factors in renal transplant recipients: a single-center study in northern Iran.
Transplantation 98(1) , 66-71, (2014) Hyperhomocysteinemia (hyperHcy) is an important risk factor for atherosclerosis, which is currently a major cause of death in renal transplant patients (RTRs). The aim of this study was to determine the associated factors of hyperHcy in RTRs in northern Iran.... |