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甲醇

一般危化品
甲醇结构式
甲醇结构式
常用名 甲醇 英文名 Methanol
CAS号 67-56-1 分子量 32.042
密度 0.8±0.1 g/cm3 沸点 48.1±3.0 °C at 760 mmHg
分子式 CH4O 熔点 -98ºC
MSDS 中文版 美版 闪点 11.1±0.0 °C
符号 GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
信号词 Danger

BBS4 directly affects proliferation and differentiation of adipocytes.

Cell. Mol. Life Sci. 71(17) , 3381-92, (2014)

BBS4 is one of several proteins whose defects cause Bardet-Biedl syndrome (BBS), a multi-systemic disorder, manifesting with marked obesity. BBS4 polymorphisms have been associated with common non-syndromic morbid obesity. BBS4 obesity molecular mechanisms, a...

Urinary metabolic fingerprinting of mice with diet-induced metabolic derangements by parallel dual secondary column-dual detection two-dimensional comprehensive gas chromatography.

J. Chromatogr. A. 1361 , 265-76, (2014)

This study investigates the potential of a parallel dual secondary column-dual detection two-dimensional comprehensive GC platform (GC×2GC-MS/FID) for metabolic profiling and fingerprinting of mouse urine. Samples were obtained from a murine model that mimics...

Biomolecular imaging with a C60-SIMS/MALDI dual ion source hybrid mass spectrometer: instrumentation, matrix enhancement, and single cell analysis.

J. Am. Soc. Mass Spectrom. 25(11) , 1897-907, (2014)

We describe a hybrid MALDI/C(60)-SIMS Q-TOF mass spectrometer and corresponding sample preparation protocols to image intact biomolecules and their fragments in mammalian spinal cord, individual invertebrate neurons, and cultured neuronal networks. A lateral ...

Synergistic activity of tenofovir and nevirapine combinations released from polycaprolactone matrices for potential enhanced prevention of HIV infection through the vaginal route.

Eur. J. Pharm. Biopharm. 88(2) , 406-14, (2014)

Polycaprolactone (PCL) matrices were simultaneously loaded with the antiviral agents, tenofovir (TFV) and nevirapine (NVP), in combination to provide synergistic activity in the prevention of HIV transmission through the vaginal route. TFV and NVP were incorp...

Antinematode activity of Violacein and the role of the insulin/IGF-1 pathway in controlling violacein sensitivity in Caenorhabditis elegans.

PLoS ONE 9(10) , e109201, (2014)

The purple pigment violacein is well known for its numerous biological activities including antibacterial, antiviral, antiprotozoan, and antitumor effects. In the current study we identify violacein as the antinematode agent produced by the marine bacterium M...

The dual FAAH/MAGL inhibitor JZL195 has enhanced effects on endocannabinoid transmission and motor behavior in rats as compared to those of the MAGL inhibitor JZL184.

Pharmacol. Biochem. Behav. 124 , 153-9, (2014)

The biological actions of the endocannabinoids anandamide and 2-arachidonoyl glycerol (2-AG) are terminated by enzymatic hydrolysis of these lipids via fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), respectively. While several selective...

Profiling of regioisomeric triacylglycerols in edible oils by supercritical fluid chromatography/tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 966 , 193-9, (2014)

In this study, supercritical fluid chromatography (SFC) coupled with triple quadrupole mass spectrometry was applied to the profiling of several regioisomeric triacylglycerols (TAGs). SFC conditions (column, flow rate, modifier) were optimized for the effecti...

Anaphylaxis induced by a drug containing lysozyme and papain: influence of papain on the IgE response.

Int. Arch. Allergy Immunol. 165(2) , 83-90, (2014)

This paper reports the case of an egg-allergic pediatric patient who, once desensitized to egg following a successful rush oral immunotherapy protocol, could also tolerate Lizipaina®, a drug containing lysozyme (LYS) and papain, which had previously caused hi...

Quantification of furanic derivatives in fortified wines by a highly sensitive and ultrafast analytical strategy based on digitally controlled microextraction by packed sorbent combined with ultrahigh pressure liquid chromatography.

J. Chromatogr. A. 1381 , 54-63, (2015)

An improved, reliable and powerful analytical strategy based on digitally controlled microextraction by packed sorbent (MEPS) combined with ultrahigh pressure liquid chromatography (UHPLC) was validated for the simultaneous identification and quantification o...

Use of an enzyme-assisted method to improve protein extraction from olive leaves.

Food Chem. 169 , 28-33, (2014)

The improvement of protein extraction from olive leaves using an enzyme-assisted protocol has been investigated. Using a cellulase enzyme (Celluclast® 1.5L), different parameters that affect the extraction process, such as the influence and amount of organic ...