1,1,1-三氟丙酮(TFK)

一般危化品
1,1,1-三氟丙酮(TFK)结构式
1,1,1-三氟丙酮(TFK)结构式
常用名 1,1,1-三氟丙酮(TFK) 英文名 1,1,1-Trifluoroacetone
CAS号 421-50-1 分子量 112.050
密度 1.2±0.1 g/cm3 沸点 21.5±0.0 °C at 760 mmHg
分子式 C3H3F3O 熔点 -78 °C
MSDS 中文版 美版 闪点 -30.6±0.0 °C
符号 GHS02 GHS07
GHS02, GHS07
信号词 Danger

Mitochondrial dysfunction and respiratory chain defects in a rodent model of methotrexate-induced enteritis.

Hum. Exp. Toxicol. 33(10) , 1051-65, (2014)

The efficacy of methotrexate (MTX), a widely used chemotherapeutic drug, is limited by its gastrointestinal toxicity and the mechanism of which is not clear. The present study investigates the possible role of mitochondrial damage in MTX-induced enteritis. Sm...

Concise synthesis of enantiopure alpha-trifluoromethyl alanines, diamines, and amino alcohols via the Strecker-type reaction.

J. Org. Chem. 71 , 7075, (2006)

Diastereomerically pure alpha-trifluoromethyl alpha-amino nitriles obtained by Strecker-type reactions from chiral CF3 imines and iminium proved to be very attractive versatile intermediates for the synthesis of various alpha-trifluoromethyl amino compounds. ...

Synthesis , 251, (2007)