5-氨基-1-萘磺酸结构式
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常用名 | 5-氨基-1-萘磺酸 | 英文名 | 1-naphthylamine-5-sulfonic acid |
|---|---|---|---|---|
| CAS号 | 84-89-9 | 分子量 | 223.248 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | N/A | |
| 分子式 | C10H9NO3S | 熔点 | >300°C | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS05, GHS07 |
信号词 | Danger |
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Identification of a novel ligand binding motif in the transthyretin channel.
Bioorg. Med. Chem. 18 , 100-10, (2010) The design of therapeutic compounds targeting transthyretin (TTR) is challenging due to the low specificity of interaction in the hormone binding site. Such feature is highlighted by the interactions of TTR with diclofenac, a compound with high affinity for T... |
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[An interesting peroxidase staining.--utilization of blended substrate of mixed 2, 7-FDA and Laurent's acid-- (author's transl)].
Rinsho Byori. 29(6) , 613-6, (1981)
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Evidence for a ppGpp-binding site on Escherichia coli RNA polymerase: proximity relationship with the rifampicin-binding domain.
Mol. Microbiol. 15(2) , 255-65, (1995) On amino acid starvation, Escherichia coli cells exhibit an adaptive facility termed the stringent response. This is characterized by the production of high levels of a regulatory nucleotide, ppGpp, and concomitant curtailment in rRNA synthesis. Various studi... |
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Controlling {beta}-amyloid oligomerization by the use of naphthalene sulfonates: trapping low molecular weight oligomeric species.
J. Biol. Chem. 280(41) , 34747-54, (2005) Aggregation of proteins and peptides has been shown to be responsible for several diseases known as amyloidoses, which include Alzheimer disease (AD), prion diseases, among several others. AD is a neurodegenerative disorder caused primarily by the aggregation... |
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Nucleotide modification at the gamma-phosphate leads to the improved fidelity of HIV-1 reverse transcriptase.
Nucleic Acids Res. 33(15) , 4865-73, (2005) The mechanism by which HIV-1 reverse transcriptase (HIV-RT) discriminates between the correct and incorrect nucleotide is not clearly understood. Chemically modified nucleotides containing 1-aminonaphthalene-5-sulfonate (ANS) attached to their gamma-phosphate... |
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Interactions of pyridoxal kinase and aspartate aminotransferase emission anisotropy and compartmentation studies.
J. Biol. Chem. 263(27) , 13712-7, (1988) Physical interactions between pyridoxal kinase and aspartate aminotransferase were detected by means of emission anisotropy and affinity chromatography techniques. Binding of aspartate aminotransferase (apoenzymes) to pyridoxal kinase tagged with a fluorescen... |
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Fluorescence of intramolecular and intermolecular interactions of aminonaphthyl-sulfonate with nucleotides.
Eur. J. Biochem. 126(2) , 367-72, (1982) Fluorescence studies of the intramolecular and intermolecular interactions between aminonaphthylsulfonate and nucleotides of uracil or adenine are described. The fluorescence originates solely from the naphthyl moiety and is intramolecularly quenched by the b... |
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Synthesis and characterization of fluorescent dinucleotide substrate for the DNA-dependent RNA polymerase from Escherichia coli.
J. Biol. Chem. 262(22) , 10684-8, (1987) New fluorescent derivatives of dinucleoside monophosphates, (5'-AmNS)UpA/ApU/GpU/CpA, with a fluorophore, 1-aminonaphthalene-5-sulfonic acid (AmNS), attached to the first nucleotide of the dinucleoside monophosphates via a 5'-secondary amine linkage were synt... |
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Fluorescent nucleotide triphosphate substrates for snake venom phosphodiesterase.
Anal. Biochem. 127(1) , 81-8, (1982)
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Synthesis and characterization of stacked and quenched uridine nucleotide fluorophores.
J. Biol. Chem. 274(21) , 14568-72, (1999) Intramolecular aromatic interactions in aqueous solution often lead to stacked conformation for model organic molecules. This designing principle was used to develop stacked and folded uridine nucleotide analogs that showed highly quenched fluoroscence in aqu... |