((1R)-1-((2S)-2-Aminopropionamido)ethyl)phosphonic acid结构式
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常用名 | ((1R)-1-((2S)-2-Aminopropionamido)ethyl)phosphonic acid | 英文名 | Alafosfalin |
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| CAS号 | 60668-24-8 | 分子量 | 196.14100 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C5H13N2O4P | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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In vitro potentiation of cephalosporins by alafosfalin against urinary tract bacteria.
Antimicrob. Agents Chemother. 21(5) , 706-10, (1982) Potentiating activity of alafosfalin was examined in detail with 8 cephalosporins and mecillinam against 164 urinary bacteria representing 8 genera. Alafosfalin was generally comparable in activity to cefamandole and mecillinam but superior to other cephalosp... |
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Alafosfalin as a selective agent for isolation of salmonella from clinical samples.
J. Clin. Microbiol. 40(11) , 3913-6, (2002) The selectivity of a range of culture media for the detection of Salmonella was assessed using 435 strains of gram-negative bacteria. These media showed limited ability to inhibit non-Salmonella strains found in stool samples. We report the evaluation of alaf... |
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Synergistic antibacterial activity between L-norvalyl-L-1-aminoethylphosphonic acid and nocardicin A.
Antimicrob. Agents Chemother. 25(5) , 607-11, (1984) The phosphonopeptide L- norvalyl -L-1- aminoethylphosphonic acid [ Nva -Ala(P)] has been studied in combination with 12 beta-lactam antibiotics for activity against Pseudomonas aeruginosa. Nocardicin A was found to give the most potent synergistic combination... |
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In vitro evaluation of alaphosphin (Ro 03-7008) against Serratia marcescens.
Chemotherapy 26(2) , 103-10, (1980) Alaphosphin (Ro 03--7008; S-alanyl-R-1-aminoethyl-phosphonic acid) proved active against most of 53 strains of Serratia marcescens tested. The majority of strains were inhibited by less than or equal to 64 micrograms/ml of the drug; concentrations of greater ... |
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Alafosfalin, a new synthetic antibacterial compound.
Naturwissenschaften 68(2) , 90, (1981)
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Recent developments in the field of phosphonic acid antibiotics.
J. Antimicrob. Chemother. 14(4) , 309-11, (1984)
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Phosphonopeptides as antibacterial agents: mechanism of action of alaphosphin.
Antimicrob. Agents Chemother. 15 , 696 - 705, (1979) The novel antibacterial peptide mimetic alaphosphin (l-alanyl-l-1-aminoethylphosphonic acid) selectively inhibited peptidoglycan biosynthesis in both gram-negative and gram-positive bacteria. It induced accumulation of uridine diphosphate-N-acetyl-muramyl-tri... |
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Phosphonopeptides, a new class of synthetic antibacterial agents.
Nature 272 , 56, (1978)
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Synthesis and structure-activity relationships of antibacterial phosphonopeptides incorporating (1-aminoethyl)phosphonic acid and (aminomethyl)phosphonic acid.
J. Med. Chem. 29 , 29, (1986) Phosphonodipeptides and phosphonooligopeptides based on L- and D-(1-aminoethyl)phosphonic acids L-Ala(P) and D-Ala(P) and (aminomethyl)phosphonic acid Gly(P) at the acid terminus have been synthesized and investigated as antibacterial agents, which owe their ... |
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[Antibiotics of the phosphonic acid group].
Antibiot. Med. Biotekhnol. 32(1) , 66-75, (1987)
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