6-甲氧基-8-硝基喹啉
6-甲氧基-8-硝基喹啉结构式
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常用名 | 6-甲氧基-8-硝基喹啉 | 英文名 | 6-Methoxy-8-nitroquinoline |
|---|---|---|---|---|
| CAS号 | 85-81-4 | 分子量 | 204.182 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 373.1±27.0 °C at 760 mmHg | |
| 分子式 | C10H8N2O3 | 熔点 | 158-160 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 179.4±23.7 °C | |
| 符号 |
GHS07, GHS08 |
信号词 | Warning |
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Ring-substituted quinolines as potential anti-tuberculosis agents.
Bioorg. Med. Chem. 12(10) , 2501-8, (2004) We report in vitro antimycobacterial properties of ring-substituted quinolines (series 1-4) constituting 56 analogues against drug-sensitive and drug-resistant M. tuberculosis H37Rv strains. The most effective compounds 2h (R1 = R2 = c-C6H11, R3 = NO2, series... |
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Primaquine-induced hemolytic anemia: formation and hemotoxicity of the arylhydroxylamine metabolite 6-methoxy-8-hydroxylaminoquinoline.
J. Pharmacol. Exp. Ther. 297(2) , 509-15, (2001) Primaquine is an important antimalarial agent because of its activity against exoerythrocytic forms of Plasmodium spp. However, methemoglobinemia and hemolytic anemia are dose-limiting side effects of primaquine therapy that limit its efficacy. These hemotoxi... |
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