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4-溴-2-硝基苯酚

4-溴-2-硝基苯酚结构式
4-溴-2-硝基苯酚结构式
品牌特惠专场
常用名 4-溴-2-硝基苯酚 英文名 4-Bromo-2-nitrophenol
CAS号 7693-52-9 分子量 218.005
密度 1.9±0.1 g/cm3 沸点 259.4±20.0 °C at 760 mmHg
分子式 C6H4BrNO3 熔点 90-94 °C(lit.)
MSDS 中文版 美版 闪点 110.7±21.8 °C
符号 GHS07
GHS07
信号词 Warning

FXR agonist activity of conformationally constrained analogs of GW 4064.

Bioorg. Med. Chem. Lett. 19(16) , 4733-9, (2009)

Two series of conformationally constrained analogs of the FXR agonist GW 4064 1 were prepared. Replacement of the metabolically labile stilbene with either benzothiophene or naphthalene rings led to the identification of potent full agonists 2a and 2g.