(R)-2-((叔丁氧基羰基)氨基)-3-((3-硝基吡啶-2-基)二硫烷基)丙酸
(R)-2-((叔丁氧基羰基)氨基)-3-((3-硝基吡啶-2-基)二硫烷基)丙酸结构式
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常用名 | (R)-2-((叔丁氧基羰基)氨基)-3-((3-硝基吡啶-2-基)二硫烷基)丙酸 | 英文名 | Boc-Cys(NPys)-OH |
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| CAS号 | 76880-29-0 | 分子量 | 375.421 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 553.9±50.0 °C at 760 mmHg | |
| 分子式 | C13H17N3O6S2 | 熔点 | -160ºC (dec.) | |
| MSDS | 中文版 美版 | 闪点 | 288.8±30.1 °C |
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Controlled peptide-protein conjugation by means of 3-nitro-2-pyridinesulfenyl protection-activation.
Int. J. Pept. Protein Res. 32(3) , 161-6, (1988) The disulfide bond in S-3-nitro-2-pyridinesulfenyl (S-Npys) compounds is stable towards the acid treatment used in solid-phase peptide synthesis, yet the liability of S-Npys-peptides towards nucleophiles enables the conjugation to proteins to proceed under mi... |
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Preparation of Boc-[S-(3-nitro-2-pyridinesulfenyl)]-cysteine and its use for unsymmetrical disulfide bond formation.
Int. J. Pept. Protein Res. 28(2) , 107-12, (1986) The 3-nitro-2-pyridinesulfenyl (Npys) derivative of cysteine was prepared and used to facilitate the formation of an unsymmetrical disulfide bond. Since this derivative is stable in trifluoroacetic acid:CH2 Cl2 (1:1) and anhydrous hydrogen fluoride, Boc-Cys(N... |
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Effects of sulfhydryl-modifying reagents, 3-nitro-2-pyridinesulfenyl compounds, on the coupling between inhibitory receptors and GTP-binding proteins Gi/Go in rat brain membranes.
Mol. Pharmacol. 38(2) , 184-91, (1990) To gain insight into the coupling mechanism of inhibitory receptors, 5-hydroxytryptamine1A receptors and alpha 2-adrenoceptors, with GTP-binding proteins (G proteins) in the central nervous system, we examined the effects of two 3-nitro-2-pyridinesulfenyl com... |
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Boc-Cys(Npys)-OH (BCNP): an appropriate reagent for the identification of T cell epitopes in cystine and/or cysteine-containing proteins.
J. Immunol. Methods 171(1) , 65-71, (1994) Some T cell epitopes become inactive when their thiols are blocked with various irreversible reagents (Régnier-Vigouroux, 1988; Maillère, 1992; Maillère et al., 1993). Blocking protein and peptide thiols with BCNP (Boc-Cys(Npys)-OH) constitutes a most appropr... |