![]() 克拉维酸钾结构式
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常用名 | 克拉维酸钾 | 英文名 | Clavulanate potassium |
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CAS号 | 61177-45-5 | 分子量 | 237.251 | |
密度 | N/A | 沸点 | 545.8ºC at 760 mmHg | |
分子式 | C8H8KNO5 | 熔点 | >1600C (dec) | |
MSDS | 中文版 美版 | 闪点 | 283.9ºC | |
符号 |
![]() ![]() GHS02, GHS08 |
信号词 | Danger |
Antibiotics for acute otitis media: yes or no.
JAMA 313(3) , 294-5, (2015)
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The NOTA Study (Non Operative Treatment for Acute Appendicitis): prospective study on the efficacy and safety of antibiotics (amoxicillin and clavulanic acid) for treating patients with right lower quadrant abdominal pain and long-term follow-up of conservatively treated suspected appendicitis.
Ann. Surg. 260(1) , 109-17, (2014) To assess the safety and efficacy of antibiotics treatment for suspected acute uncomplicated appendicitis and to monitor the long term follow-up of non-operated patients.Right lower quadrant abdominal pain is a common cause of emergency department admission. ... |
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Effect of antimicrobial treatment of acute otitis media on the daily disappearance of middle ear effusion: a placebo-controlled trial.
JAMA Pediatr. 168(7) , 635-41, (2014) Antimicrobial treatment reduces the symptoms of acute otitis media (AOM). The effect of antimicrobial treatment on the duration of middle ear effusion (MEE) and concomitant hearing impairment is not known.To determine whether the antimicrobial treatment of AO... |
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Implant survival rate and marginal bone loss of 6-mm short implants: a 2-year clinical report.
Int. J. Oral Maxillofac. Implants 29(6) , 1425-8, (2014) This study aimed to evaluate (1) the association between implant diameter and marginal bone loss (MBL) of short (6 mm) implants and (2) the survival rates of short implants.Thirty-three 6-mm implants were placed in the mandibles of 16 qualified patients. The ... |
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Rickettsia parkeri rickettsiosis in different ecological regions of Argentina and its association with Amblyomma tigrinum as a potential vector.
Am. J. Trop. Med. Hyg. 91(6) , 1156-60, (2014) Rickettsia parkeri, a newly recognized tick-borne pathogen of humans in the Americas, is a confirmed cause of spotted fever group rickettsiosis in Argentina. Until recently, almost all cases of R. parkeri rickettsiosis in Argentina have originated from the Pa... |
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Solid-state stability and compatibility studies of clavulanate potassium.
Pharm. Dev. Technol. 20(2) , 146-52, (2015) The kinetic and thermodynamic parameters of degradation of clavulanate potassium in the solid state were studied by using a reversed phase high performance liquid chromatography (RP-HPLC) method. The degradation of clavulanate potassium was a first-order reac... |
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Identification of peptide inhibitors of penicillinase using a phage display library.
Anal. Biochem. 494 , 4-9, (2015) There is a constant need to identify novel inhibitors to combat β-lactamase-mediated antibiotic resistance. In this study, we identify three penicillinase-binding peptides, P1 (DHIHRSYRGEFD), P2 (NIYTTPWGSNWS), and P3 (SHSLPASADLRR), using a phage display lib... |
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Unilateral acute dacryocystitis associated with oculoglandular tularemia: a case report.
Semin. Ophthalmol. 28(2) , 91-3, (2013) To describe an unusual case of oculoglandular tularemia associated with unilateral acute dacryocystitis and purulent conjunctivitis with 18 weeks pregnancy.It is difficult to culture francisella tularensis on media so serological tests such as micro-agglutina... |
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Simultaneous quantification of cefpodoxime proxetil and clavulanic acid in human plasma by LC-MS using solid phase extraction with application to pharmacokinetic studies.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 921-922 , 49-55, (2013) A simple, rapid and selective high performance liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry (HPLC-APCI-MS) method was developed and validated for the simultaneous estimation of cefpodoxime proxetil (CDPX) and clavulanic aci... |
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Drug-induced liver injury.
Mayo Clin. Proc. 89(1) , 95-106, (2014) Drug hepatoxicity can be nonidiosyncratic (predictable), as in the case of acetaminophen, or idiosyncratic (unpredictable). This review article focuses primarily on idiosyncratic drug-induced liver injury (DILI). New epidemiologic data suggest that approximat... |