氯甲酸异丁酯
一般危化品
氯甲酸异丁酯结构式
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常用名 | 氯甲酸异丁酯 | 英文名 | Isobutyl chloroformate |
|---|---|---|---|---|
| CAS号 | 543-27-1 | 分子量 | 136.577 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 130.0±0.0 °C at 760 mmHg | |
| 分子式 | C5H9ClO2 | 熔点 | -80°C | |
| MSDS | 中文版 美版 | 闪点 | 27.8±0.0 °C | |
| 符号 |
GHS02, GHS05, GHS06 |
信号词 | Danger |
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A new analytical method to determine non-steroidal anti-inflammatory drugs in surface water using in situ derivatization combined with ultrasound-assisted emulsification microextraction followed by gas chromatography-mass spectrometry.
Talanta 129 , 552-9, (2014) Because of the high stability and potential toxic effects of non-steroidal anti-inflammatory drugs (NSAIDs), it is important to closely monitor their concentrations in the environment using a sensitive analytical method. In this study, a simple, rapid, effici... |
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Homogeneous detection of caspase-3 using intrinsic fluorescence resonance energy transfer (iFRET).
Biosens. Bioelectron. 67 , 413-8, (2015) Caspase-3 is an apoptotic cysteine protease and its aberrancy is highly implicated to numerous diseases thereby rendering caspase-3 activity as an important disease marker. Most caspase-3 sensors are caspase-3 substrates of which the fluorescence signals are ... |
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Design, synthesis and biological evaluation of novel pyrenyl derivatives as anticancer agents.
Eur. J. Med. Chem. 89 , 851-62, (2014) Polycyclic aromatic hydrocarbons are widespread in nature with a toxicity range from non-toxic to extremely toxic. A series of pyrenyl derivatives has been synthesized following a four-step strategy where the pyrene nucleus is attached with a basic heterocycl... |
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Preparation and Characterization of a Monoclonal Antibody Against Morphine.
Monoclon. Antib. Immunodiagn. Immunother. 34 , 270-4, (2015) A monoclonal antibody (MAb) was produced by immunization of a BALB/c mouse with a conjugated morphine C6-hemisuccinated derivative (MHS) to cationized bovine serum albumin (cBSA). The hybridoma clones were screened by indirect ELISA using MHS-BSA. The best hy... |
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Preparation of intravenous injection nanoformulation of VESylated gemcitabine by co-assembly with TPGS and its anti-tumor activity in pancreatic tumor-bearing mice.
Int. J. Pharm. 495 , 792-7, (2015) Our recent publication showed that VES-dFdC nanocapsules in pure water could be obtained via the self-assembling of VES-dFdC prodrug synthesized by coupling gemcitabine (dFdC) with vitamin E succinate (VES). To prepare the intravenous injection nanoformulatio... |
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Hapten synthesis, monoclonal antibody production and development of a competitive indirect enzyme-linked immunosorbent assay for erythromycin in milk.
Food Chem. 171 , 98-107, (2014) Erythromycin is an antibiotic used extensively in veterinary practice worldwide for treatment, prevention and growth promotion. In this work, monoclonal antibodies (Mabs) against erythromycin were produced and used to develop a competitive indirect enzyme-lin... |
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Capillary gas chromatographic analysis of protein amino acids as their N(O,S)-isobutoxycarbonyl methyl ester derivatives.
Biomed. Chromatogr. 9(5) , 205-10, (1995) A simple and rapid method for the determination of the 22 protein amino acids by capillary gas chromatography is described. The amino acids were converted into their N(O,S)-isobutoxycarbonyl (isoBOC) methyl ester derivatives and measured by GC with flame ioni... |
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Unprecedented crystallization and X-ray crystal structure of racemic N(alpha)-(t-butyloxycarbonyl)-L-L-phenylalanine N-methoxy-N-methylamide.
Chirality 12(1) , 2-6, (2000) Weinreb amide 3 was synthesized using isobutyl chloroformate, carbonyldiimidazole, or ethylcarbodiimide as the coupling agent in the reaction of Boc-phenylalanine with O,N-dimethylhydroxylamine hydrochloride. An optically active oil was isolated along with an... |
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Gas chromatographic determination of primary and secondary low-molecular-mass aliphatic amines in urine using derivatization with isobutyl chloroformate.
J. Chromatogr. A. 617(2) , 191-6, (1993) A simple routine method for the gas chromatographic determination of methylamine, dimethylamine, ethylamine and methylethylamine in urine is presented. The method is based on a two-phase derivatization procedure with isobutyl chloroformate as reagent. The rea... |
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A fast derivatization procedure for gas chromatographic analysis of perfluorinated organic acids.
J. Chromatogr. A. 1216(49) , 8659-64, (2009) A rapid and simple derivatization procedure has been developed for gas chromatographic determination of perfluorinated organic acids (PFCAs, C(6)-C(12)), using isobutyl chloroformate (IBCF) to convert the acids into the more volatile isobutyl esters, under ca... |