4,7-二羟基香豆素
4,7-二羟基香豆素结构式
|
常用名 | 4,7-二羟基香豆素 | 英文名 | 2H-1-Benzopyran-2-one,4,7-dihydroxy- |
|---|---|---|---|---|
| CAS号 | 1983-81-9 | 分子量 | 178.14200 | |
| 密度 | 1.612g/cm3 | 沸点 | 390ºC at 760mmHg | |
| 分子式 | C9H6O4 | 熔点 | 263 °C(dec.) | |
| MSDS | 中文版 美版 | 闪点 | 166.5ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Multiple UDP-glucuronosyltransferases in human liver microsomes glucuronidate both R- and S-7-hydroxywarfarin into two metabolites.
Arch. Biochem. Biophys. 564 , 244-53, (2014) The widely used anticoagulant Coumadin (R/S-warfarin) undergoes oxidation by cytochromes P450 into hydroxywarfarins that subsequently become conjugated for excretion in urine. Hydroxywarfarins may modulate warfarin metabolism transcriptionally or through dire... |
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