2H-1-Benzopyran-2-one,4,7-dihydroxy-

2H-1-Benzopyran-2-one,4,7-dihydroxy- Structure
2H-1-Benzopyran-2-one,4,7-dihydroxy- structure
Common Name 2H-1-Benzopyran-2-one,4,7-dihydroxy-
CAS Number 1983-81-9 Molecular Weight 178.14200
Density 1.612g/cm3 Boiling Point 390ºC at 760mmHg
Molecular Formula C9H6O4 Melting Point 263 °C(dec.)
MSDS Chinese USA Flash Point 166.5ºC
Symbol GHS07
GHS07
Signal Word Warning

Multiple UDP-glucuronosyltransferases in human liver microsomes glucuronidate both R- and S-7-hydroxywarfarin into two metabolites.

Arch. Biochem. Biophys. 564 , 244-53, (2014)

The widely used anticoagulant Coumadin (R/S-warfarin) undergoes oxidation by cytochromes P450 into hydroxywarfarins that subsequently become conjugated for excretion in urine. Hydroxywarfarins may modulate warfarin metabolism transcriptionally or through dire...