胰激肽释放酶
胰激肽释放酶结构式
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常用名 | 胰激肽释放酶 | 英文名 | Kallikrein |
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| CAS号 | 9001-01-8 | 分子量 | 283.277 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 471.1±45.0 °C at 760 mmHg | |
| 分子式 | C13H17NO6 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 238.7±28.7 °C |
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BMPR2 is required for postimplantation uterine function and pregnancy maintenance.
J. Clin. Invest. 123(6) , 2539-50, (2013) Abnormalities in cell-cell communication and growth factor signaling pathways can lead to defects in maternal-fetal interactions during pregnancy, including immunologic rejection of the fetal/placental unit. In this study, we discovered that bone morphogeneti... |
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The structure of human microplasmin in complex with textilinin-1, an aprotinin-like inhibitor from the Australian brown snake.
PLoS ONE 8(1) , e54104, (2013) Textilinin-1 is a Kunitz-type serine protease inhibitor from Australian brown snake venom. Its ability to potently and specifically inhibit human plasmin (K(i) = 0.44 nM) makes it a potential therapeutic drug as a systemic anti-bleeding agent. The crystal str... |
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Neutron and X-ray crystallographic analysis of Achromobacter protease I at pD 8.0: protonation states and hydration structure in the free-form.
Biochim. Biophys. Acta 1834(8) , 1642-7, (2013) The structure of the free-form of Achromobacter protease I (API) at pD 8.0 was refined by simultaneous use of single crystal X-ray and neutron diffraction data sets to investigate the protonation states of key catalytic residues of the serine protease. Occupa... |
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Intraocular hemorrhage causes retinal vascular dysfunction via plasma kallikrein.
Invest. Ophthalmol. Vis. Sci. 54(2) , 1086-94, (2013) Retinal hemorrhages occur in a variety of sight-threatening conditions including ocular trauma, high altitude retinopathy, and chronic diseases such as diabetic and hypertensive retinopathies. The goal of this study is to investigate the effects of blood in t... |
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Clinical response to crizotinib retreatment after acquisition of drug resistance.
J. Clin. Oncol. 31(19) , e322-3, (2013)
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PCSK9 and the road less traveled: how an unconventional approach led to a major discovery.
Clin. Chem. 59(8) , 1283-4, (2013)
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The kallikreins: old proteases with new clinical potentials.
Thromb. Haemost. 110(3) , 396-8, (2013)
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Role the TICE?: advancing the concept of transintestinal cholesterol excretion.
Arterioscler. Thromb. Vasc. Biol. 33(7) , 1452-3, (2013)
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Structure of plasma and tissue kallikreins.
Thromb. Haemost. 110(3) , 423-33, (2013) The kallikrein kinin system (KKS) consists of serine proteases involved in the production of peptides called kinins, principally bradykinin and Lys-bradykinin (kallidin). The KKS contributes to a variety of physiological processes including inflammation, bloo... |
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Diversity of human plasma protein C inhibitor.
Thromb. Res. 130(4) , 661-6, (2012) Protein C inhibitor was purified from human plasma by use of a dermatan sulfate or heparin column, followed by hydroxyapatite, gel filtration and ion exchange columns. A dimer of protein C inhibitor was detected by SDS-PAGE under reducing conditions, in addit... |