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4-苄基苯酚

4-苄基苯酚结构式
4-苄基苯酚结构式
品牌特惠专场
常用名 4-苄基苯酚 英文名 4-Benzylphenol
CAS号 101-53-1 分子量 184.234
密度 1.1±0.1 g/cm3 沸点 321.9±11.0 °C at 760 mmHg
分子式 C13H12O 熔点 79-81 °C(lit.)
MSDS 中文版 美版 闪点 154.2±11.1 °C
符号 GHS07
GHS07
信号词 Warning

Surfactants, aromatic and isoprenoid compounds, and fatty acid biosynthesis inhibitors suppress Staphylococcus aureus production of toxic shock syndrome toxin 1.

Antimicrob. Agents Chemother. 53 , 1898-906, (2009)

Menstrual toxic shock syndrome is a rare but potentially life-threatening illness manifest through the actions of Staphylococcus aureus toxic shock syndrome toxin 1 (TSST-1). Previous studies have shown that tampon additives can influence staphylococcal TSST-...

Identification and characterization of novel sirtuin inhibitor scaffolds.

Bioorg. Med. Chem. 17 , 7031-41, (2009)

The sirtuin proteins are broadly conserved NAD(+)-dependent deacetylases that are implicated in diverse biological processes including DNA recombination and repair, transcriptional silencing, longevity, apoptosis, axonal protection, insulin signaling, and fat...

Method development for impurity profiling in SFC: The selection of a dissimilar set of stationary phases.

J. Pharm. Biomed. Anal. 111 , 333-43, (2015)

Supercritical fluid chromatography (SFC) is drawing considerable interest as separation technique in the pharmaceutical industry. The technique is already well established in chiral separations both analytically and on a preparative scale. The use of SFC as a...

Semi-quantitative profile of regioisomeric monohydroxydiphenylmethane metabolites in rat urine, faeces and bile.

Xenobiotica 11(6) , 425-32, (1981)

1. Urine and faeces, and two-hour bile samples from adult male rats dosed with [14C]diphenylmethane were analysed for benzhydrol and 2- and 4-hydroxydiphenyl-methane by silica gel GF t.l.c. and 14C-determination. 2. Mean values of 48.4% and 17.7% of the admin...

Genotoxic activation of benzophenone and its two metabolites by human cytochrome P450s in SOS/umu assay.

Mutat. Res. 519(1-2) , 199-204, (2002)

The genotoxic potential of benzophenone and its metabolically related compounds, benzhydrol and p-benzoylphenol, was investigated using human cytochrome P450 (P450) enzymes. Benzophenone and its two metabolites (0.1-1mM) showed a suppression of bacterial grow...

Ligands to the (IRAP)/AT4 receptor encompassing a 4-hydroxydiphenylmethane scaffold replacing Tyr2

Bioorg. Med. Chem. 16 , 6924-35, (2008)

Analogues of the hexapeptide angiotensin IV (Ang IV, Val(1)-Tyr(2)-Ile(3)-His(4)-Pro(5)-Phe(6)) encompassing a 4-hydroxydiphenylmethane scaffold replacing Tyr(2) and a phenylacetic or benzoic acid moiety replacing His(4)-Pro(5)-Phe(6) have been synthesized an...