4-Benzylphenol
4-Benzylphenol structure
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Common Name | 4-Benzylphenol | ||
|---|---|---|---|---|
| CAS Number | 101-53-1 | Molecular Weight | 184.234 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 321.9±11.0 °C at 760 mmHg | |
| Molecular Formula | C13H12O | Melting Point | 79-81 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 154.2±11.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Surfactants, aromatic and isoprenoid compounds, and fatty acid biosynthesis inhibitors suppress Staphylococcus aureus production of toxic shock syndrome toxin 1.
Antimicrob. Agents Chemother. 53 , 1898-906, (2009) Menstrual toxic shock syndrome is a rare but potentially life-threatening illness manifest through the actions of Staphylococcus aureus toxic shock syndrome toxin 1 (TSST-1). Previous studies have shown that tampon additives can influence staphylococcal TSST-... |
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Identification and characterization of novel sirtuin inhibitor scaffolds.
Bioorg. Med. Chem. 17 , 7031-41, (2009) The sirtuin proteins are broadly conserved NAD(+)-dependent deacetylases that are implicated in diverse biological processes including DNA recombination and repair, transcriptional silencing, longevity, apoptosis, axonal protection, insulin signaling, and fat... |
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Method development for impurity profiling in SFC: The selection of a dissimilar set of stationary phases.
J. Pharm. Biomed. Anal. 111 , 333-43, (2015) Supercritical fluid chromatography (SFC) is drawing considerable interest as separation technique in the pharmaceutical industry. The technique is already well established in chiral separations both analytically and on a preparative scale. The use of SFC as a... |
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Semi-quantitative profile of regioisomeric monohydroxydiphenylmethane metabolites in rat urine, faeces and bile.
Xenobiotica 11(6) , 425-32, (1981) 1. Urine and faeces, and two-hour bile samples from adult male rats dosed with [14C]diphenylmethane were analysed for benzhydrol and 2- and 4-hydroxydiphenyl-methane by silica gel GF t.l.c. and 14C-determination. 2. Mean values of 48.4% and 17.7% of the admin... |
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Genotoxic activation of benzophenone and its two metabolites by human cytochrome P450s in SOS/umu assay.
Mutat. Res. 519(1-2) , 199-204, (2002) The genotoxic potential of benzophenone and its metabolically related compounds, benzhydrol and p-benzoylphenol, was investigated using human cytochrome P450 (P450) enzymes. Benzophenone and its two metabolites (0.1-1mM) showed a suppression of bacterial grow... |
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Ligands to the (IRAP)/AT4 receptor encompassing a 4-hydroxydiphenylmethane scaffold replacing Tyr2
Bioorg. Med. Chem. 16 , 6924-35, (2008) Analogues of the hexapeptide angiotensin IV (Ang IV, Val(1)-Tyr(2)-Ile(3)-His(4)-Pro(5)-Phe(6)) encompassing a 4-hydroxydiphenylmethane scaffold replacing Tyr(2) and a phenylacetic or benzoic acid moiety replacing His(4)-Pro(5)-Phe(6) have been synthesized an... |