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4-甲基硫代苯甲酰胺

4-甲基硫代苯甲酰胺结构式
4-甲基硫代苯甲酰胺结构式
品牌特惠专场
常用名 4-甲基硫代苯甲酰胺 英文名 4-Methylbenzenecarbothioamide
CAS号 2362-62-1 分子量 151.229
密度 1.1±0.1 g/cm3 沸点 258.9±33.0 °C at 760 mmHg
分子式 C8H9NS 熔点 163-168 °C
MSDS 中文版 美版 闪点 110.4±25.4 °C
符号 GHS07
GHS07
信号词 Warning

Determination of p-methylthiobenzamide and p-methylthiobenzamide-S-oxide from rat plasma using solid-phase extraction and high-performance liquid chromatography.

J. Chromatogr. A. 567(1) , 213-20, (1991)

p-Methylthiobenzamide (PMTB) is a thiocarbonyl compound exhibiting marked hepatotoxicity and nephrotoxicity. We describe a high-performance liquid chromatographic method for analyzing PMTB and a metabolite, p-methylthiobenzamide-S-oxide (PMTBSO), from rat pla...

The effect of partial hepatectomy on the metabolism, distribution, and nephrotoxicity of para-methylthiobenzamide in the rat.

Toxicol. Appl. Pharmacol. 113(2) , 246-52, (1992)

Para-Methylthiobenzamide (PMTB) produces injury to the liver and kidney. Toxicity is mediated via its biotransformation to a reactive S,S-dioxide metabolite. The objective of this study was to examine the role of hepatic metabolism in the production of PMTB-i...