4-Methylbenzenecarbothioamide
4-Methylbenzenecarbothioamide structure
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Common Name | 4-Methylbenzenecarbothioamide | ||
|---|---|---|---|---|
| CAS Number | 2362-62-1 | Molecular Weight | 151.229 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 258.9±33.0 °C at 760 mmHg | |
| Molecular Formula | C8H9NS | Melting Point | 163-168 °C | |
| MSDS | Chinese USA | Flash Point | 110.4±25.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Determination of p-methylthiobenzamide and p-methylthiobenzamide-S-oxide from rat plasma using solid-phase extraction and high-performance liquid chromatography.
J. Chromatogr. A. 567(1) , 213-20, (1991) p-Methylthiobenzamide (PMTB) is a thiocarbonyl compound exhibiting marked hepatotoxicity and nephrotoxicity. We describe a high-performance liquid chromatographic method for analyzing PMTB and a metabolite, p-methylthiobenzamide-S-oxide (PMTBSO), from rat pla... |
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The effect of partial hepatectomy on the metabolism, distribution, and nephrotoxicity of para-methylthiobenzamide in the rat.
Toxicol. Appl. Pharmacol. 113(2) , 246-52, (1992) Para-Methylthiobenzamide (PMTB) produces injury to the liver and kidney. Toxicity is mediated via its biotransformation to a reactive S,S-dioxide metabolite. The objective of this study was to examine the role of hepatic metabolism in the production of PMTB-i... |
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