ABT-418 hydrochloride
ABT-418 hydrochloride结构式
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常用名 | ABT-418 hydrochloride | 英文名 | 3-Methyl-5-[(2S)-1-methyl-2-pyrrolidinyl]isoxazole hydrochloride |
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| CAS号 | 147388-83-8 | 分子量 | 202.68100 | |
| 密度 | N/A | 沸点 | 249.2ºC at 760 mmHg | |
| 分子式 | C9H15ClN2O | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 104.5ºC | |
| 符号 |
GHS06 |
信号词 | Danger |
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Alzheimer's disease therapy - an update.
Drug News Perspect. 11 , 248-55, (1998) The 5th International Geneva/Springfield Symposium on Advances in Alzheimer Therapy focused on new therapeutic approaches for the treatment of Alzheimer 's disease (AD) based on the latest basic science data. The two major pharmacological principles of cholin... |
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Anxiolytic-like effects of the novel cholinergic channel activator ABT-418.
J. Pharmacol. Exp. Ther. 271 , 353-61, (1994) The hydrochloride salt of (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT-418), a potent activator of select subtypes of neuronal nicotinic acetylcholine receptors enhanced retention in memory tests and induced anxiolytic-like effects in mice in the e... |
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ABT-418: discriminative stimulus properties and effect on ventral tegmental cell activity.
Psychopharmacology 119 , 368-75, (1995) Previous studies have established that ABT-418 [(S)-3-methyl-5-(1 methyl-2-pyrrolidinyl)isoxazole hydrochloride] is a novel neuronal nicotinic acetylcholine receptor (nAChR) ligand with cognitive enhancing and anxiolytic-like activity 3- to 10-fold more poten... |