3-Methyl-5-[(2S)-1-methyl-2-pyrrolidinyl]isoxazole hydrochloride

3-Methyl-5-[(2S)-1-methyl-2-pyrrolidinyl]isoxazole hydrochloride Structure
3-Methyl-5-[(2S)-1-methyl-2-pyrrolidinyl]isoxazole hydrochloride structure
Common Name 3-Methyl-5-[(2S)-1-methyl-2-pyrrolidinyl]isoxazole hydrochloride
CAS Number 147388-83-8 Molecular Weight 202.68100
Density N/A Boiling Point 249.2ºC at 760 mmHg
Molecular Formula C9H15ClN2O Melting Point N/A
MSDS Chinese USA Flash Point 104.5ºC
Symbol GHS06
GHS06
Signal Word Danger

Alzheimer's disease therapy - an update.

Drug News Perspect. 11 , 248-55, (1998)

The 5th International Geneva/Springfield Symposium on Advances in Alzheimer Therapy focused on new therapeutic approaches for the treatment of Alzheimer 's disease (AD) based on the latest basic science data. The two major pharmacological principles of cholin...

Anxiolytic-like effects of the novel cholinergic channel activator ABT-418.

J. Pharmacol. Exp. Ther. 271 , 353-61, (1994)

The hydrochloride salt of (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT-418), a potent activator of select subtypes of neuronal nicotinic acetylcholine receptors enhanced retention in memory tests and induced anxiolytic-like effects in mice in the e...

ABT-418: discriminative stimulus properties and effect on ventral tegmental cell activity.

Psychopharmacology 119 , 368-75, (1995)

Previous studies have established that ABT-418 [(S)-3-methyl-5-(1 methyl-2-pyrrolidinyl)isoxazole hydrochloride] is a novel neuronal nicotinic acetylcholine receptor (nAChR) ligand with cognitive enhancing and anxiolytic-like activity 3- to 10-fold more poten...