N-苄氧羰基甘氨酸
N-苄氧羰基甘氨酸结构式
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常用名 | N-苄氧羰基甘氨酸 | 英文名 | Z-Gly-OH |
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| CAS号 | 1138-80-3 | 分子量 | 209.199 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 424.0±38.0 °C at 760 mmHg | |
| 分子式 | C10H11NO4 | 熔点 | 118-122 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 210.2±26.8 °C |
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Anticonvulsant activities of N-benzyloxycarbonylglycine after parenteral administration.
Neuroreport 5(7) , 777-80, (1994) Although glycine does not cross easily the blood-brain barrier, it exhibits at very high doses (10-40 mmol kg-1) a modest anticonvulsant activity. In this study, carbamate derivatives--N-benzyloxycarbonylglycine (Z-glycine) and N,tert-butoxycarbonylglycine (B... |
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Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM).
Bioorg. Med. Chem. 16 , 10061-74, (2008) Peptidyl alpha-hydroxylating monooxygenase (PHM) functions in vivo towards the biosynthesis of alpha-amidated peptide hormones in mammals and insects. PHM is a potential target for the development of inhibitors as drugs for the treatment of human disease and ... |
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Synthesis and anticonvulsant activity of N-benzyloxycarbonyl-amino acid prodrugs of phenytoin.
J. Pharm. Pharmacol. 51 , 549-553, (1999) Glycine, which has weak anticonvulsant properties, has been shown to potentiate the activity of several antiepileptic drugs but not phenytoin. Recently, studies have shown that N-(benzyloxycarbonyl)glycine (Z-glycine) antagonized seizures more than glycine in... |
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Duality of mechanism in the tetramethylfluoroformamidinium hexafluorophosphate-mediated synthesis of N-benzyloxycarbonylamino acid fluorides.
J. Org. Chem. 66(17) , 5905-10, (2001)
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