Z-Gly-OH

Z-Gly-OH Structure
Z-Gly-OH structure
Common Name Z-Gly-OH
CAS Number 1138-80-3 Molecular Weight 209.199
Density 1.3±0.1 g/cm3 Boiling Point 424.0±38.0 °C at 760 mmHg
Molecular Formula C10H11NO4 Melting Point 118-122 °C(lit.)
MSDS Chinese USA Flash Point 210.2±26.8 °C

Anticonvulsant activities of N-benzyloxycarbonylglycine after parenteral administration.

Neuroreport 5(7) , 777-80, (1994)

Although glycine does not cross easily the blood-brain barrier, it exhibits at very high doses (10-40 mmol kg-1) a modest anticonvulsant activity. In this study, carbamate derivatives--N-benzyloxycarbonylglycine (Z-glycine) and N,tert-butoxycarbonylglycine (B...

Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM).

Bioorg. Med. Chem. 16 , 10061-74, (2008)

Peptidyl alpha-hydroxylating monooxygenase (PHM) functions in vivo towards the biosynthesis of alpha-amidated peptide hormones in mammals and insects. PHM is a potential target for the development of inhibitors as drugs for the treatment of human disease and ...

Synthesis and anticonvulsant activity of N-benzyloxycarbonyl-amino acid prodrugs of phenytoin.

J. Pharm. Pharmacol. 51 , 549-553, (1999)

Glycine, which has weak anticonvulsant properties, has been shown to potentiate the activity of several antiepileptic drugs but not phenytoin. Recently, studies have shown that N-(benzyloxycarbonyl)glycine (Z-glycine) antagonized seizures more than glycine in...

Duality of mechanism in the tetramethylfluoroformamidinium hexafluorophosphate-mediated synthesis of N-benzyloxycarbonylamino acid fluorides.

J. Org. Chem. 66(17) , 5905-10, (2001)