2-氟-4-甲基苯胺
2-氟-4-甲基苯胺结构式
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常用名 | 2-氟-4-甲基苯胺 | 英文名 | 2-fluoro-4-methyl-aniline |
|---|---|---|---|---|
| CAS号 | 452-80-2 | 分子量 | 125.144 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 196.5±0.0 °C at 760 mmHg | |
| 分子式 | C7H8FN | 熔点 | 3 °C | |
| MSDS | 中文版 美版 | 闪点 | 79.4±0.0 °C | |
| 符号 |
GHS06 |
信号词 | Danger |
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Synthesis of chiral building blocks for use in drug discovery.
Molecules 9(6) , 405-26, (2004) In the past decade there has been a significant growth in the sales of pharmaceutical drugs worldwide, but more importantly there has been a dramatic growth in the sales of single enantiomer drugs. The pharmaceutical industry has a rising demand for chiral in... |
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Rat liver microsomal metabolism of 2-halogenated 4-methylanilines.
Xenobiotica 22(12) , 1403-23, (1992) 1. Rat liver microsomal metabolism of 2-fluoro-, 2-chloro- and 2-bromo-4-methylaniline was investigated using h.p.l.c. Metabolites identified include products from side-chain C-hydroxylation (benzyl alcohols and benzaldehydes) and N-hydroxylation (hydroxylami... |
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Indoline derivatives as 5-HT(2C) receptor agonists.
Bioorg. Med. Chem. Lett. 14 , 2367-2370, (2004) A series of 1-(1-indolinyl)-2-propylamines was synthesised and evaluated as 5-HT(2C) receptor agonists for the treatment of obesity. The general methods of synthesis of the precursor indoles are described. The functional efficacy and radioligand binding data ... |