二氢硫辛酸
二氢硫辛酸结构式
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常用名 | 二氢硫辛酸 | 英文名 | Dihydrolipoic acid |
|---|---|---|---|---|
| CAS号 | 462-20-4 | 分子量 | 208.341 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 360.8±32.0 °C at 760 mmHg | |
| 分子式 | C8H16O2S2 | 熔点 | 60ºC | |
| MSDS | 中文版 美版 | 闪点 | 172.0±25.1 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Wash-free magnetic immunoassay of the PSA cancer marker using SERS and droplet microfluidics.
Lab Chip 16 , 1022-9, (2016) We report a novel wash-free magnetic immunoassay technique for prostate-specific antigen (PSA) that uses a surface-enhanced Raman scattering (SERS)-based microdroplet sensor. The magnetic bar embedded in a droplet-based microfluidic system segregates the free... |
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Delivery and tracking of quantum dot peptide bioconjugates in an intact developing avian brain.
ACS Chem. Neurosci. 6(3) , 494-504, (2015) Luminescent semiconductor ∼9.5 nm nanoparticles (quantum dots: QDs) have intrinsic physiochemical and optical properties which enable us to begin to understand the mechanisms of nanoparticle mediated chemical/drug delivery. Here, we demonstrate the ability of... |
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Colloidal stability of gold nanoparticles modified with thiol compounds: bioconjugation and application in cancer cell imaging.
Langmuir 28(9) , 4464-71, (2012) Gold nanoparticles (GNPs) are attractive alternative optical probes and good biocompatible materials due to their special physical and chemical properties. However, GNPs have a tendency to aggregate particularly in the presence of high salts and certain biolo... |
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Natural compound Alternol induces oxidative stress-dependent apoptotic cell death preferentially in prostate cancer cells.
Mol. Cancer Ther. 13(6) , 1526-36, (2014) Prostate cancers at the late stage of castration resistance are not responding well to most of current therapies available in clinic, reflecting a desperate need of novel treatment for this life-threatening disease. In this study, we evaluated the anticancer ... |
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α-Lipoic acid inhibits liver fibrosis through the attenuation of ROS-triggered signaling in hepatic stellate cells activated by PDGF and TGF-β.
Toxicology 282(1-2) , 39-46, (2011) Reactive oxygen species (ROS) have been implicated in hepatic stellate cell activation and liver fibrosis. We previously reported that α-lipoic acid (LA) and its reduced form dihydrolipoic acid (DHLA) inhibited toxicant-induced inflammation and ROS generation... |
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Microwave-assisted rapid synthesis of luminescent gold nanoclusters for sensing Hg2+ in living cells using fluorescence imaging.
Nanoscale 4(14) , 4155-60, (2012) A microwave-assisted strategy for synthesizing dihydrolipoic acid (DHLA) capped fluorescent gold nanoclusters (AuNCs) has been developed. Irradiation with microwaves during synthesis enhanced the fluorescence quantum yield (QY) of AuNCs by about five-fold and... |
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On the pH-dependent quenching of quantum dot photoluminescence by redox active dopamine.
J. Am. Chem. Soc. 134(13) , 6006-17, (2012) We investigated the charge transfer interactions between luminescent quantum dots (QDs) and redox active dopamine. For this, we used pH-insensitive ZnS-overcoated CdSe QDs rendered water-compatible using poly (ethylene glycol)-appended dihydrolipoic acid (DHL... |
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Multifunctional compact zwitterionic ligands for preparing robust biocompatible semiconductor quantum dots and gold nanoparticles.
J. Am. Chem. Soc. 133(24) , 9480-96, (2011) We describe the synthesis of a series of four different ligands which are used to prepare hydrophilic, biocompatible luminescent quantum dots (QDs) and gold nanoparticles (AuNPs). Overall, the ligands are designed to be compact while still imparting a zwitter... |
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Water-soluble semiconductor nanocrystals cap exchanged with metalated ligands.
ACS Nano 5(1) , 546-50, (2011) We report a novel method for cap exchange of emissive semiconductor nanocrystals (NCs) using thiol functional ligands metalated with zinc. Utilizing this method, the NCs can be several times brighter and much more resistant to precipitation compared to contro... |
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Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide.
Biochem. J. 439(3) , 479-85, (2011) H2S (hydrogen sulfide) has recently been recognized as a signalling molecule as well as a cytoprotectant. We recently demonstrated that 3MST (3-mercaptopyruvate sulfurtransferase) produces H2S from 3MP (3-mercaptopyruvate). Although a reducing substance is re... |