L-哌啶酸
L-哌啶酸结构式
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常用名 | L-哌啶酸 | 英文名 | L(-)-Pipecolinic acid |
|---|---|---|---|---|
| CAS号 | 3105-95-1 | 分子量 | 129.157 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 265.8±33.0 °C at 760 mmHg | |
| 分子式 | C6H11NO2 | 熔点 | 272ºC | |
| MSDS | 中文版 美版 | 闪点 | 114.5±25.4 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
Bioorg. Med. Chem. 19 , 6409-18, (2011) The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitative structure-activity relationship (3D QSAR) study has been... |
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Lysine catabolism in Haemonchus contortus and Teladorsagia circumcincta.
Exp. Parasitol. 131(1) , 101-6, (2012) Catabolism of lysine through the pipecolate, saccharopine and cadaverine pathways has been investigated in L3 and adult Haemonchus contortus and Teladorsagia circumcincta. Both enzymes of the saccharopine pathway (lysine ketoglutarate reductase (LKR) and sacc... |
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Characterization of the nocardiopsin biosynthetic gene cluster reveals similarities to and differences from the rapamycin and FK-506 pathways.
ChemBioChem. 16(6) , 990-7, (2015) Macrolide-pipecolate natural products, such as rapamycin (1) and FK-506 (2), are renowned modulators of FK506-binding proteins (FKBPs). The nocardiopsins, from Nocardiopsis sp. CMB-M0232, are the newest members of this structural class. Here, the biosynthetic... |
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Effect of a carboxyl group on the chemiluminescent reaction of tris(2,2′-bipyridine)ruthenium(III) with aliphatic amines
Talanta 78(1) , 227-32, (2009) The effect of a carboxyl group beside nitrogen of aliphatic amines on the tris(2,2′-bipyridine)ruthenium(III), Ru(bpy) 3 3+, chemiluminescent reaction was examined. It has been shown that a carboxylate anion promotes the chemiluminescent reaction at a lower p... |
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Determination of pipecolic acid following trimethylsilyl and trifluoroacyl derivatisation on plasma filter paper by stable isotope GC-MS for peroxisomal disorders.
Arch. Pharm. Res. 33(2) , 317-23, (2010) If early diagnosis is not made, patients with peroxisomal disorders rapidly progress to sudden death, physical defect or mental retardation resulted in storage of the toxic material into the brain. Therefore, it is necessary to develop the analytical method f... |
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Lysine restricted diet for pyridoxine-dependent epilepsy: first evidence and future trials.
Mol. Genet. Metab. 107(3) , 335-44, (2012) To evaluate the efficacy and safety of dietary lysine restriction as an adjunct to pyridoxine therapy on biochemical parameters, seizure control, and developmental/cognitive outcomes in children with pyridoxine-dependent epilepsy (PDE) caused by antiquitin (A... |
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Peroxisomal bifunctional enzyme deficiency.
J. Clin. Invest. 83(3) , 771-7, (1989) Peroxisomal function was evaluated in a male infant with clinical features of neonatal adrenoleukodystrophy. Very long chain fatty acid levels were elevated in both plasma and fibroblasts, and beta-oxidation of very long chain fatty acids in cultured fibrobla... |
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Algicidal activity of a dibenzofuran-degrader Rhodococcus sp.
J. Microbiol. Biotechnol. 23(2) , 260-6, (2013) Rhodococcus sp. strain p52, a previously isolated dibenzofuran degrader, could effectively inhibit the growth of cyanobacteria, including species of Microcystis, Anabaena, and Nodularia. When strain p52 was inoculated at the concentration of 7.7×10(7) CFU/ml,... |
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Stereoselective analysis of D and L dansyl amino acids as the mixed chelate copper(II) complexes by HPLC.
J. Chromatogr. Sci. 22(9) , 416-23, (1984) This paper reviews the mixed chelation approach to resolution of the optical isomers of D and L dansyl amino acids by high performance liquid chromatography. The use of eluants containing Cu(II) complexes of L-proline, L-arginine, L-histidine, and L-histidine... |
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An efficient lipase-catalyzed enantioselective hydrolysis of (R,S)-azolides derived from N-protected proline, pipecolic acid, and nipecotic acid.
Appl. Microbiol. Biotechnol. 97(4) , 1581-7, (2013) In the Candida antarctica lipase B-catalyzed hydrolysis of (R,S)-azolides derived from (R,S)-N-protected proline in water-saturated methyl tert-butyl ether (MTBE), high enzyme activity with excellent enantioselectivity (V (S) V (R) (-1) > 100) for (R,S)-N-Cb... |