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2,2'-二硫二吡啶

2,2'-二硫二吡啶结构式
2,2'-二硫二吡啶结构式
品牌特惠专场
常用名 2,2'-二硫二吡啶 英文名 2,2′-Dipyridyl disulfide
CAS号 2127-03-9 分子量 220.31
密度 1.3±0.1 g/cm3 沸点 356.1±17.0 °C at 760 mmHg
分子式 C10H8N2S2 熔点 56-58 °C(lit.)
MSDS 中文版 美版 闪点 169.2±20.9 °C
符号 GHS07
GHS07
信号词 Warning

Clay catalyzed RNA synthesis under Martian conditions: Application for Mars return samples.

Biochem. Biophys. Res. Commun. 462 , 99-104, (2015)

Catalysis by montmorillonites clay minerals is regarded as a feasible mechanism for the abiotic production and polymerization of key biomolecules on early Earth. We have investigated a montmorillonite-catalyzed reaction of the 5'-phosphorimidazolide of nucleo...

Development of an enzymatic assay system of D-lactate using D-lactate dehydrogenase and a UV-LED fluorescent spectrometer.

J. Pharm. Biomed. Anal. 116 , 150-5, (2015)

In this study, we aimed to develop a new enzymatic assay system of d-lactate with good precision, accuracy, and sensitivity for the determination of D-lactate concentrations in rat serum. D-Lactate dehydrogenase (D-LDH) was utilized to catalyze D-lactate and ...

The RimL transacetylase provides resistance to translation inhibitor microcin C.

J. Bacteriol. 196(19) , 3377-85, (2014)

Peptide-nucleotide antibiotic microcin C (McC) is produced by some Escherichia coli strains. Inside a sensitive cell, McC is processed, releasing a nonhydrolyzable analog of aspartyl-adenylate, which inhibits aspartyl-tRNA synthetase. The product of mccE, a g...

Immobilization of FLAG-Tagged Recombinant Adeno-Associated Virus 2 onto Tissue Engineering Scaffolds for the Improvement of Transgene Delivery in Cell Transplants.

PLoS ONE 10 , e0129013, (2015)

The technology of virus-based genetic modification in tissue engineering has provided the opportunity to produce more flexible and versatile biomaterials for transplantation. Localizing the transgene expression with increased efficiency is critical for tissue...

SIKVAV-modified highly superporous PHEMA scaffolds with oriented pores for spinal cord injury repair.

J. Tissue Eng. Regen. Med. 9 , 1298-309, (2015)

The architecture and mechanical properties of a scaffold for spinal cord injury treatment must provide tissue integration as well as effective axonal regeneration. Previous work has demonstrated the cell-adhesive and growth-promoting properties of the SIKVAV ...

Novel free-paclitaxel-loaded redox-responsive nanoparticles based on a disulfide-linked poly(ethylene glycol)-drug conjugate for intracellular drug delivery: synthesis, characterization, and antitumor activity in vitro and in vivo.

Mol. Pharm. 11(10) , 3656-70, (2014)

To address the obstacles facing cancer chemotherapeutics, including toxicity, side effects, water insolubility, and lack of tumor selectivity, a novel stimuli-responsive drug-delivery system was developed based on paclitaxel-loaded poly(ethylene glycol)-disul...

Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing.

Methods 44(1) , 3-12, (2008)

Distinct classes of small RNAs, 20-32 nucleotides long, play important regulatory roles for diverse cellular processes. It is therefore important to identify and quantify small RNAs as a function of development, tissue and cell type, in normal and disease sta...

Pyruvate prevents the development of age-dependent cognitive deficits in a mouse model of Alzheimer's disease without reducing amyloid and tau pathology.

Neurobiol. Dis. 81 , 214-24, (2015)

Amyloid-β (Aβ) deposition and tau-dependent pathology are key features of Alzheimer's disease (AD). However, to date, approaches aimed at counteracting these two pathogenic factors have produced only modest therapeutic outcomes. More effective therapies shoul...

The identification of disulfides in ricin D using proteolytic cleavage followed by negative-ion nano-electrospray ionization mass spectrometry of the peptide fragments.

Rapid Commun. Mass Spectrom. 29(2) , 182-90, (2015)

To use negative-ion nano-electrospray ionization mass spectrometry of peptides from the tryptic digest of ricin D, to provide sequence information; in particular, to identify disulfide position and connectivity.Negative-ion fragmentations of peptides from the...

Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: Impact of the carrier structure onto synergistic action in the treatment of solid tumours.

Eur. J. Pharm. Sci. 58 , 1-12, (2014)

In this study, we describe the synthesis, physico-chemical characterisation and results of the in vitro and in vivo evaluation of the biological behaviour of N-(2-hydroxypropyl)methacrylamide-based (HPMA) copolymer conjugates bearing doxorubicin (DOX) partly ...